Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   FWK49_RS02090 Genome accession   NZ_CP042988
Coordinates   454876..455982 (+) Length   368 a.a.
NCBI ID   WP_075294326.1    Uniprot ID   A0A9Q6Z044
Organism   Histophilus somni strain UOC-KLM-ATR-09     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 449876..460982
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FWK49_RS02065 (FWK49_02065) - 450729..450803 (-) 75 Protein_397 aspartate kinase -
  FWK49_RS02070 (FWK49_02070) proA 450865..452121 (-) 1257 WP_011608564.1 glutamate-5-semialdehyde dehydrogenase -
  FWK49_RS02075 (FWK49_02075) - 452131..452802 (-) 672 WP_011608565.1 trimeric intracellular cation channel family protein -
  FWK49_RS02080 (FWK49_02080) - 452963..453550 (-) 588 WP_011608566.1 thymidine kinase -
  FWK49_RS02085 (FWK49_02085) tsaD 453612..454640 (-) 1029 WP_011608567.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD -
  FWK49_RS02090 (FWK49_02090) dprA 454876..455982 (+) 1107 WP_075294326.1 DNA-processing protein DprA Machinery gene
  FWK49_RS02095 (FWK49_02095) rsmD 455965..456567 (-) 603 WP_011608569.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  FWK49_RS02100 (FWK49_02100) pilA 456631..457974 (+) 1344 WP_136122076.1 signal recognition particle-docking protein FtsY Machinery gene
  FWK49_RS02105 (FWK49_02105) murJ 458137..459708 (-) 1572 WP_075294324.1 murein biosynthesis integral membrane protein MurJ -
  FWK49_RS02110 (FWK49_02110) rpsT 459986..460249 (+) 264 WP_011608572.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 368 a.a.        Molecular weight: 41519.72 Da        Isoelectric Point: 6.5011

>NTDB_id=333616 FWK49_RS02090 WP_075294326.1 454876..455982(+) (dprA) [Histophilus somni strain UOC-KLM-ATR-09]
MDKRNELLLRLLQVPKLGASGITQLLSHIDLKTLEDYDDVAFHYLGWKPEQINRWLYPDLRYIEPALFWASKKGHYLMNF
YQENYPYLLKQTIGAPPLLFIKGNPEILAQQQVAIVGSRHCSHYGEYWAKYFATELFLAGFVITSGLALGIDGFCHQAVV
DIQGQTIGVLGGGLEELYPKQHKKLAQQMLDYGGALVSEFLPHQPPKPQHFPQRNRIISGLSKGVLVVEATEKSGSLITA
RYALEQNREVFALPGQIQNEYSQGCHRLIKDGALLVENVADIVENLSPFTHYERQLTAKQIETQFPPAYKLPASPTYPEL
YAHIGYTPVGLDELSNKSGLSVDTLLIQLLELELQDLVIAEKGLYRRT

Nucleotide


Download         Length: 1107 bp        

>NTDB_id=333616 FWK49_RS02090 WP_075294326.1 454876..455982(+) (dprA) [Histophilus somni strain UOC-KLM-ATR-09]
ATGGATAAACGGAATGAGCTGTTACTGCGTTTGTTACAAGTGCCGAAGTTGGGAGCGTCCGGAATAACTCAACTTTTATC
ACACATCGATTTAAAAACATTAGAGGATTATGATGATGTTGCGTTTCATTATTTAGGCTGGAAACCTGAACAGATAAATA
GATGGTTGTATCCGGATCTTAGATATATTGAACCTGCATTATTTTGGGCAAGCAAAAAGGGACATTATTTGATGAATTTC
TATCAAGAGAATTACCCTTATTTATTAAAGCAAACCATAGGTGCTCCCCCTTTGTTATTTATCAAAGGCAATCCGGAAAT
ACTTGCTCAACAACAAGTCGCTATTGTAGGAAGCCGTCATTGCTCACATTATGGCGAGTATTGGGCAAAGTATTTTGCAA
CGGAATTGTTCCTTGCCGGTTTTGTTATTACCAGTGGACTGGCTCTAGGGATAGACGGTTTTTGTCATCAGGCTGTTGTG
GATATTCAAGGACAAACTATCGGGGTATTAGGGGGAGGTTTGGAAGAGTTGTATCCCAAACAACATAAAAAATTAGCACA
ACAAATGCTAGATTATGGCGGTGCGTTAGTGTCAGAATTTTTACCTCATCAGCCTCCCAAACCACAACATTTTCCTCAAC
GTAATCGCATTATTAGCGGACTTTCTAAAGGTGTTTTAGTGGTTGAGGCAACAGAAAAAAGCGGTTCACTCATTACTGCA
CGTTATGCTTTAGAACAAAATAGAGAAGTTTTTGCACTTCCAGGACAAATTCAAAATGAGTATAGTCAAGGGTGTCATAG
ATTAATAAAAGACGGTGCGTTGTTAGTAGAGAATGTTGCAGATATTGTAGAAAATTTATCGCCTTTTACGCATTATGAAC
GTCAACTAACAGCAAAACAGATAGAAACGCAATTTCCGCCGGCTTATAAGTTACCTGCTTCACCGACTTATCCTGAACTC
TATGCCCATATTGGTTATACGCCGGTAGGGCTTGATGAATTATCAAATAAAAGCGGATTAAGTGTAGATACCTTATTGAT
ACAGCTGTTAGAACTTGAATTGCAAGATCTCGTTATTGCTGAAAAAGGGTTATATCGACGGACTTAA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(310-361)

DNA recombination-mediator protein A (DNA_processg_A)

(71-277)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A9Q6Z044

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Haemophilus influenzae Rd KW20

61.126

100

0.62
  dprA Glaesserella parasuis strain SC1401

50.432

94.293

0.476
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

44.986

100

0.451
  dprA Vibrio cholerae strain A1552

44.986

100

0.451
  dprA Vibrio campbellii strain DS40M4

41.096

99.185

0.408
  dprA Legionella pneumophila strain ERS1305867

38.798

99.457

0.386