Detailed information NTG0331375

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: EJF26_RS07465
• Genome accession: NZ_CP034442
• Coordinates: 1484908..1487061 (+)
• Length: 717 a.a.
• NCBI ID: WP_000668250.1
• Uniprot ID: -
• Organism: Streptococcus oralis subsp. dentisani strain F0392
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1479908..1492061

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EJF26_RS07415	recO	1480270..1481040 (+)	771	WP_000616134.1	DNA repair protein RecO	-
EJF26_RS07420	plsX	1481037..1482029 (+)	993	WP_000717469.1	phosphate acyltransferase PlsX	-
EJF26_RS07425	-	1482034..1482270 (+)	237	WP_000136440.1	acyl carrier protein	-
EJF26_RS07430	-	1482600..1482743 (+)	144	WP_000180834.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
EJF26_RS07435	-	1482759..1482917 (+)	159	WP_001056955.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
EJF26_RS09850	-	1483314..1483469 (+)	156	WP_000732133.1	hypothetical protein	-
EJF26_RS07440	-	1483508..1483720 (+)	213	WP_001016295.1	hypothetical protein	-
EJF26_RS07445	-	1483801..1483989 (+)	189	WP_000808741.1	hypothetical protein	-
EJF26_RS07450	-	1484014..1484223 (+)	210	WP_000869802.1	hypothetical protein	-
EJF26_RS10320	-	1484548..1484742 (+)	195	WP_001033679.1	hypothetical protein	-
EJF26_RS07465	comA	1484908..1487061 (+)	2154	WP_000668250.1	peptide cleavage/export ABC transporter ComA	Regulator
EJF26_RS07470	comB	1487074..1488423 (+)	1350	WP_001182201.1	competence pheromone export protein ComB	Regulator
EJF26_RS07475	purC	1488591..1489298 (+)	708	WP_000032091.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80220.49 Da
• Isoelectric Point: 6.8324

>NTDB_id=331375 EJF26_RS07465 WP_000668250.1 1484908..1487061(+) (comA) [Streptococcus oralis subsp. dentisani strain F0392]
MKFGKKHYRPQVDQMDCGVASLAMIFSYYGSYYSLAHLRELAKTTMDGTTALGLVKVAEELGFETRAIKADMTLFDLPDL
TFPFVAHVLKEGKLLHYYVVTGQDKKTIHIADPDPGVKLTKISRERFAQEWTGISLFMAPSPDYKPHKEKKQGLLSFLPI
LLKQHGLITNIVLATLLVTLINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLVLGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTILIISLVLFSQNMTLFFISLLALPIYTV
IIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESSCYQKIDKEFVAYLKKSFTYSRAESQQKALKKVAQL
LLNVGVLWLGAILVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEKKTVEDLSMM
KGEMTFKQVHYKYGYGRDVLSDINLTIPQGSKMAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGANLNQIDKKALRQYI
NYLPQQPYVFNGTILENLLLGAKEGTTQEDVLRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLVFIAHRLTIAERTEKVVVLDQGKIIEEGTHADLLARGGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=331375 EJF26_RS07465 WP_000668250.1 1484908..1487061(+) (comA) [Streptococcus oralis subsp. dentisani strain F0392]
ATGAAATTTGGGAAAAAACACTATCGTCCTCAGGTGGATCAGATGGATTGCGGCGTGGCTTCCTTGGCTATGATATTTAG
CTACTACGGTAGTTATTACTCCTTGGCTCATCTACGAGAGTTGGCCAAGACGACCATGGATGGGACGACTGCTTTGGGGC
TTGTAAAGGTGGCAGAGGAGCTTGGCTTTGAGACGCGGGCTATCAAGGCGGATATGACGCTCTTTGATCTGCCTGATTTG
ACCTTTCCTTTTGTGGCCCATGTGCTCAAGGAAGGGAAATTGCTCCACTACTATGTGGTGACAGGTCAGGATAAGAAGAC
CATCCATATCGCTGATCCAGATCCTGGTGTCAAGCTGACTAAGATTTCTCGTGAGCGATTTGCGCAAGAGTGGACAGGGA
TCAGTCTCTTTATGGCGCCATCTCCAGACTATAAACCCCATAAGGAGAAAAAACAGGGGCTCTTATCTTTCTTGCCCATC
TTACTCAAACAGCATGGCTTAATTACCAATATCGTCCTAGCGACACTCTTGGTAACCCTGATTAACATTGTGGGTTCTTA
TTATCTTCAGTCTATCATTGATACCTATGTGCCAGACCAGATGCGTTCGACACTGGGCATCATCTCTATTGGGCTGGTCA
TCGTCTATATCCTCCAGCAGATCTTGTCCTACGCGCAGGAGTATCTCTTACTTGTTTTGGGGCAACGTCTGTCAATTGAT
GTGATTTTGTCCTACATCAAGCATGTTTTTCACCTGCCAATGTCCTTTTTTGCGACACGCAGGACAGGAGAAATCGTATC
TCGTTTTACAGATGCCAATAGTATCATTGATGCGCTGGCGTCGACCATTCTGTCGATTTTCCTAGATGTGTCGACGATTT
TGATTATTTCGCTTGTCTTGTTTTCACAAAATATGACGCTCTTTTTCATTAGTCTGCTTGCGCTTCCCATCTATACAGTG
ATTATCTTTGCCTTTATGAAACCTTTTGAAAAGATGAATCGGGATACTATGGAAGCTAATGCGGTTCTGTCTTCTTCTAT
CATCGAGGACATCAACGGCATTGAGACCATTAAATCTTTGACCAGTGAGAGTTCGTGCTATCAAAAGATTGACAAGGAAT
TTGTAGCTTATCTGAAAAAATCTTTTACCTATAGTCGGGCAGAAAGCCAGCAAAAGGCTCTGAAAAAAGTTGCCCAGCTC
CTGCTCAATGTTGGTGTTCTCTGGCTGGGAGCTATTCTTGTCATGGATGGGAAAATGAGTTTGGGCCAGCTGATTACCTA
TAATACTTTGCTTGTTTACTTTACCAATCCTTTGGAAAATATCATCAACCTGCAAACCAAACTTCAGACAGCACAGGTTG
CCAATAATCGCTTAAATGAGGTTTATCTAGTAGCTTCGGAGTTTGAGGAGAAGAAAACAGTCGAAGATTTGAGCATGATG
AAGGGAGAGATGACCTTCAAGCAGGTTCACTATAAGTATGGCTATGGTCGTGACGTCTTGTCGGATATCAATTTGACCAT
TCCGCAAGGGTCTAAGATGGCTTTTGTGGGGATTTCGGGGTCAGGAAAAACCACCTTGGCCAAGATGATGGTTAATTTTT
ACGACCCAAGTCAGGGAGAGATTAGTCTGGGTGGTGCCAATCTCAATCAGATTGATAAAAAAGCCTTGCGCCAGTATATC
AACTACCTGCCTCAACAGCCCTATGTATTTAACGGAACGATTTTGGAGAATCTTCTCCTTGGAGCCAAAGAAGGGACGAC
ACAGGAGGATGTTCTGCGAGCAGTCGAGTTAGCTGAGATTCGGGAGGATATCGAGCGGATGCCACTGAATTACCAGACAG
AATTGACTTCGGATGGAGCTGGAATTTCTGGTGGGCAACGGCAGCGAATTGCTCTGGCGCGTGCTCTTTTAACAGATGCC
CCTGTCTTGATCTTGGATGAGGCAACTAGCAGTCTGGATATTTTGACAGAGAAGCGGATCGTGGATAATCTTATGGCTTT
GGACAAGACCTTGGTTTTCATTGCCCACCGCTTGACCATCGCTGAGCGGACAGAAAAGGTTGTTGTTTTGGATCAGGGCA
AGATTATCGAAGAAGGTACCCATGCAGACTTGCTTGCTCGAGGTGGATTTTACGCCCATTTGGTGAATAGCTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (500-650)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• Peptidase C39 family (Peptidase_C39) (6-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	94.142	100	0.941
comA	Streptococcus pneumoniae Rx1	93.863	100	0.939
comA	Streptococcus pneumoniae D39	93.863	100	0.939
comA	Streptococcus pneumoniae R6	93.863	100	0.939
comA	Streptococcus mitis SK321	93.863	100	0.939
comA	Streptococcus pneumoniae TIGR4	93.445	100	0.934
comA	Streptococcus gordonii str. Challis substr. CH1	80.614	100	0.806
comA/nlmT	Streptococcus mutans UA159	63.877	100	0.639