Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD   Type   Regulator
Locus tag   EJF26_RS07215 Genome accession   NZ_CP034442
Coordinates   1442796..1444115 (-) Length   439 a.a.
NCBI ID   WP_001048121.1    Uniprot ID   -
Organism   Streptococcus oralis subsp. dentisani strain F0392     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1437796..1449115
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EJF26_RS07190 - 1438480..1441134 (-) 2655 WP_000472059.1 YhgE/Pip domain-containing protein -
  EJF26_RS07195 - 1441263..1441805 (+) 543 WP_000665076.1 TetR/AcrR family transcriptional regulator -
  EJF26_RS07210 comE 1442047..1442799 (-) 753 WP_000866080.1 competence system response regulator transcription factor ComE Regulator
  EJF26_RS07215 comD 1442796..1444115 (-) 1320 WP_001048121.1 competence system sensor histidine kinase ComD Regulator
  EJF26_RS07220 comC 1444137..1444262 (-) 126 WP_000799680.1 competence-stimulating peptide ComC Regulator
  EJF26_RS07230 rlmH 1444546..1445025 (-) 480 WP_000694224.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  EJF26_RS07235 htrA 1445209..1446399 (+) 1191 WP_000681818.1 S1C family serine protease Regulator
  EJF26_RS07240 spo0J 1446457..1447215 (+) 759 WP_004246572.1 ParB/RepB/Spo0J family partition protein Regulator
  EJF26_RS07245 dnaA 1447438..1448799 (+) 1362 WP_004245972.1 chromosomal replication initiator protein DnaA -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 51333.02 Da        Isoelectric Point: 5.3406

>NTDB_id=331369 EJF26_RS07215 WP_001048121.1 1442796..1444115(-) (comD) [Streptococcus oralis subsp. dentisani strain F0392]
MNLFGLVIAFFYVFIISKIYEWTCSATKKEKYIYSLYVFLLQLILEEIMYLLALDGYGLSKFLFPLLIFGYFVGFQKYDK
SKGVFISLLFSLLYHSSNNFISVTLSSITGDDIALEYNNYFIIFVLILTYLVIKIVISYFHLEFKYFDKEYLYSFLKKVL
YAFIFLHIVSFISDIVSTISHLNSFGSILSTIVFICLLLIFFAMNSYKVQIEKEIALKQKKFEQKHLQTYTDEIVKLYNE
IRGFRHDYAGMLVSMQMAIDSEDLQEIDRVYNEVLVKANQKLRSEKYTYFDLNNLEDSALRSLIAQSIVYARNNDVEFTL
EVKDVITRLSMDLLDLVRIMSILLNNAVEGAADSYLKQMEVAVIKMDFETVIVIQNSCKITMTPSEDLFALGFSTKGRNR
GLGLNNVKEILDKYDNIMLETEMEDNTFRQIIRFKREFE

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=331369 EJF26_RS07215 WP_001048121.1 1442796..1444115(-) (comD) [Streptococcus oralis subsp. dentisani strain F0392]
ATGAATTTATTTGGATTAGTAATAGCTTTTTTTTATGTTTTTATCATTAGTAAAATTTATGAATGGACTTGTAGTGCAAC
TAAAAAAGAAAAATATATTTATAGTCTTTATGTCTTTTTACTACAATTAATATTAGAAGAAATAATGTATTTGCTAGCCT
TAGATGGTTACGGTTTGTCTAAATTTTTATTTCCTTTACTCATATTCGGTTACTTTGTTGGATTTCAGAAGTATGATAAG
TCTAAGGGAGTTTTTATAAGCCTATTATTTTCTCTCTTATATCATAGTAGTAATAACTTTATATCGGTAACTTTATCATC
TATAACAGGAGATGATATTGCATTAGAATATAATAATTATTTTATTATATTTGTACTTATTTTAACCTATTTGGTTATTA
AAATTGTCATATCTTATTTCCATTTGGAGTTTAAATATTTTGACAAAGAATATCTCTATTCTTTTTTGAAAAAAGTGCTA
TATGCATTTATCTTCTTGCATATCGTCTCTTTTATTTCAGATATCGTGAGTACTATTTCTCATTTAAATAGTTTTGGAAG
TATTTTATCAACCATTGTTTTTATTTGCTTGTTATTGATTTTCTTTGCAATGAATTCTTATAAGGTTCAAATTGAAAAAG
AGATTGCCCTAAAGCAGAAGAAATTTGAACAAAAGCATTTACAGACTTATACTGATGAAATTGTCAAGTTGTATAATGAA
ATTCGAGGTTTTCGTCATGACTATGCAGGTATGCTTGTCAGCATGCAAATGGCAATTGACAGTGAAGATTTACAGGAAAT
TGACAGAGTTTACAATGAAGTATTAGTAAAAGCGAATCAAAAACTGCGTTCAGAAAAATATACTTACTTTGATTTGAACA
ATTTAGAAGATTCAGCTTTACGTAGTTTGATTGCTCAATCCATTGTTTATGCACGAAATAATGATGTAGAGTTTACATTG
GAAGTAAAGGATGTTATTACTAGATTGTCAATGGATTTACTTGATCTTGTTCGCATCATGAGTATTCTCTTAAACAATGC
TGTTGAAGGAGCCGCGGATAGTTACTTGAAACAAATGGAAGTTGCAGTCATTAAAATGGATTTTGAGACAGTTATAGTCA
TCCAGAATTCATGTAAAATCACTATGACGCCTTCAGAGGACTTATTTGCCTTAGGTTTCTCTACCAAGGGAAGAAATAGA
GGTTTAGGGCTTAATAATGTCAAAGAGATTCTAGATAAATATGACAACATTATGTTAGAAACAGAGATGGAAGACAACAC
ATTTAGACAAATTATTAGATTTAAGAGGGAATTCGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(332-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD Streptococcus mitis SK321

72.562

100

0.729
  comD Streptococcus mitis NCTC 12261

72.336

100

0.727
  comD/comD2 Streptococcus pneumoniae TIGR4

71.202

100

0.715
  comD/comD1 Streptococcus pneumoniae R6

70.748

100

0.711
  comD/comD1 Streptococcus pneumoniae Rx1

70.748

100

0.711
  comD/comD1 Streptococcus pneumoniae D39

70.748

100

0.711
  comD/comD2 Streptococcus gordonii strain NCTC7865

48.67

85.649

0.417
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

48.396

85.194

0.412

Multiple sequence alignment