NTDB

Overview

Name	ciaR	Type	Regulator
Locus tag	FPT06_RS00905	Genome accession	NZ_CP041994
Coordinates	183148..183819 (+)	Length	223 a.a.
NCBI ID	WP_009909965.1	Uniprot ID	-
Organism	Streptococcus suis strain INT-01
Function	repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 178148..188819

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FPT06_RS00880 (FPT06_00880)	pstB	178527..179330 (+)	804	WP_002937615.1	phosphate ABC transporter ATP-binding protein PstB	-
FPT06_RS00885 (FPT06_00885)	pstB	179342..180100 (+)	759	WP_002937614.1	phosphate ABC transporter ATP-binding protein PstB	-
FPT06_RS00890 (FPT06_00890)	phoU	180129..180785 (+)	657	WP_013730396.1	phosphate signaling complex protein PhoU	-
FPT06_RS00895 (FPT06_00895)	-	180987..182189 (-)	1203	WP_002935295.1	IS110-like element ISSsu7 family transposase	-
FPT06_RS00900 (FPT06_00900)	-	182574..182954 (+)	381	WP_002935294.1	hypothetical protein	-
FPT06_RS00905 (FPT06_00905)	ciaR	183148..183819 (+)	672	WP_009909965.1	response regulator transcription factor	Regulator
FPT06_RS00910 (FPT06_00910)	ciaH	183812..185191 (+)	1380	WP_002935290.1	cell wall metabolism sensor histidine kinase WalK	Regulator
FPT06_RS00920 (FPT06_00920)	-	185515..186744 (+)	1230	WP_002935288.1	transglutaminase domain-containing protein	-
FPT06_RS00925 (FPT06_00925)	rpsT	187006..187254 (-)	249	WP_012027069.1	30S ribosomal protein S20	-
FPT06_RS00930 (FPT06_00930)	coaA	187313..188233 (-)	921	WP_002935283.1	type I pantothenate kinase	-

Sequence

Protein

Download Length: 223 a.a. Molecular weight: 25290.00 Da Isoelectric Point: 4.2183

                                >NTDB_id=329180 FPT06_RS00905 WP_009909965.1 183148..183819(+) (ciaR) [Streptococcus suis strain INT-01]

MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA

KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTFGDVTVDLSTNMTMVNGEEVELLGKEFDLLVY

FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide

Download Length: 672 bp

                                >NTDB_id=329180 FPT06_RS00905 WP_009909965.1 183148..183819(+) (ciaR) [Streptococcus suis strain INT-01]

ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCGGATGT

TATGCAGGTTTTTGATGGTGAAGAGGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTGATGT

TGCCTGAAAAAGATGGCTTCCAAGTCTTGAAAGAATTACGTGAAAAAGGTGTTACGACACCTGTTCTGATTACAACAGCC

AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGGGCTGATGACTATTTGACAAAACCGTTTTATTTAGAAGA

ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGTAAGTTTAATGAAAACACACTAACCTTTGGAGATGTGACAG

TTGACCTATCTACAAATATGACGATGGTAAATGGCGAAGAAGTTGAACTGCTAGGAAAAGAATTTGATCTACTAGTTTAT

TTCTTGCAAAATCAAAATGTTATTTTGCCAAAAACACAAATTTTTGACCGTATTTGGGGCTTTGACAGTGATACTACAAT

TTCAGTAGTAGAAGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACCTTTGGGGAAAATCTTCAAACCCTGC

GTAGTGTCGGATACATTCTAAAAAATGCCTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ciaR	Streptococcus mutans UA159	90.135	100	0.901
ciaR	Streptococcus pneumoniae Rx1	88.341	100	0.883
ciaR	Streptococcus pneumoniae D39	88.341	100	0.883
ciaR	Streptococcus pneumoniae R6	88.341	100	0.883
ciaR	Streptococcus pneumoniae TIGR4	88.341	100	0.883
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.496	100	0.39
vicR	Streptococcus mutans UA159	35.47	100	0.372
covR	Streptococcus salivarius strain HSISS4	35.841	100	0.363

Detailed information NTG0329180