Detailed information NTG0326129

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: EGX82_RS05610
• Genome accession: NZ_CP033822
• Coordinates: 1059696..1060598 (-)
• Length: 300 a.a.
• NCBI ID: WP_000912098.1
• Uniprot ID: A0AAD2WWZ7
• Organism: Streptococcus agalactiae strain FDAARGOS_512
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1054696..1065598

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGX82_RS05590 (EGX82_05590)	-	1055658..1057436 (-)	1779	WP_001220911.1	acyltransferase family protein	-
EGX82_RS05595 (EGX82_05595)	-	1057433..1057813 (-)	381	WP_000787702.1	membrane protein	-
EGX82_RS05600 (EGX82_05600)	-	1057820..1058257 (-)	438	WP_000754817.1	low molecular weight protein-tyrosine-phosphatase	-
EGX82_RS05605 (EGX82_05605)	ruvB	1058409..1059407 (-)	999	WP_000196633.1	Holliday junction branch migration DNA helicase RuvB	-
EGX82_RS05610 (EGX82_05610)	comR	1059696..1060598 (-)	903	WP_000912098.1	helix-turn-helix domain-containing protein	Regulator
EGX82_RS05615 (EGX82_05615)	purB	1060751..1062049 (-)	1299	WP_000893937.1	adenylosuccinate lyase	-
EGX82_RS05620 (EGX82_05620)	-	1062135..1063238 (-)	1104	WP_001867169.1	DUF6287 domain-containing protein	-
EGX82_RS05625 (EGX82_05625)	-	1063604..1063861 (-)	258	WP_000590468.1	hypothetical protein	-
EGX82_RS05630 (EGX82_05630)	purK	1063871..1064944 (-)	1074	WP_001048172.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
EGX82_RS05635 (EGX82_05635)	purE	1064931..1065422 (-)	492	WP_001875905.1	5-(carboxyamino)imidazole ribonucleotide mutase	-

Sequence

Protein

• Length: 300 a.a.
• Molecular weight: 35606.08 Da
• Isoelectric Point: 6.5030

>NTDB_id=326129 EGX82_RS05610 WP_000912098.1 1059696..1060598(-) (comR) [Streptococcus agalactiae strain FDAARGOS_512]
MLKHFGSKVRNLRVTRNITREDFCGDETELSVRQLARIESGQSIPNLTKAHYIAKQLNVKLDILTGGESLELPKRYKELK
YKLLRTPTYGDANRLAVREAYFDEIYEVFYEELPEDERLIIDCMQSKLDVHFSVNDNFGITILHDYFDQIKKKKEYTTND
FVMIDLYLLCFSINYGMKSLYSLENYHFIMSKLLEQDNLLPEDNFQLNNVLLNHVELAFQFKQKKYVQQIIHRSNAIMTE
IHDFQKRPILSLIEWKYLLIIEKDRTKAETCFKQSILFAELIGDLYLKGKLIEEWNKDLT

Nucleotide

• Length: 903 bp

>NTDB_id=326129 EGX82_RS05610 WP_000912098.1 1059696..1060598(-) (comR) [Streptococcus agalactiae strain FDAARGOS_512]
ATGTTAAAACATTTTGGTAGTAAAGTAAGAAATTTGAGAGTAACTAGAAATATTACTCGCGAAGATTTTTGTGGTGATGA
AACTGAGTTATCTGTAAGACAATTAGCTAGGATTGAAAGTGGACAGTCAATTCCAAACTTGACTAAAGCTCACTACATAG
CTAAACAATTGAATGTAAAATTGGATATTTTAACAGGAGGAGAGAGCTTAGAATTACCTAAACGGTATAAAGAGTTGAAG
TACAAATTGTTGCGTACCCCGACTTACGGAGATGCTAATAGACTTGCAGTTAGAGAAGCATATTTTGATGAAATCTATGA
AGTATTTTATGAGGAGCTCCCAGAAGATGAAAGACTAATTATTGATTGTATGCAATCAAAATTAGATGTTCATTTTTCTG
TTAATGATAATTTTGGAATCACTATTTTACATGACTACTTTGATCAAATTAAGAAAAAAAAGGAATATACCACAAATGAT
TTTGTTATGATAGATTTATATTTACTTTGCTTTTCTATTAACTATGGAATGAAGAGCTTGTATTCTTTAGAGAACTATCA
TTTTATTATGTCAAAATTGTTAGAGCAAGATAATTTACTTCCTGAGGATAATTTTCAATTGAACAACGTTTTATTAAATC
ATGTCGAATTAGCTTTTCAATTTAAGCAGAAAAAATATGTACAGCAAATTATTCATAGAAGTAATGCTATTATGACAGAA
ATCCATGATTTTCAAAAAAGACCAATACTAAGCTTAATAGAGTGGAAATATTTATTAATTATTGAAAAAGATAGAACAAA
AGCAGAAACATGTTTTAAACAATCAATTCTATTTGCAGAGTTAATAGGTGATCTATATTTAAAAGGAAAATTAATAGAGG
AGTGGAATAAAGATTTAACATGA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-295)

• Helix-turn-helix (HTH_3) (10-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	59.375	96	0.57
comR	Streptococcus mutans UA159	52.174	99.667	0.52
comR	Streptococcus pyogenes MGAS8232	50.166	100	0.503
comR	Streptococcus pyogenes MGAS315	47.667	100	0.477
comR	Streptococcus suis P1/7	40.067	99	0.397
comR	Streptococcus suis 05ZYH33	40.067	99	0.397
comR	Streptococcus suis D9	36.184	100	0.367