Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   EGX85_RS01585 Genome accession   NZ_CP033814
Coordinates   308985..309851 (-) Length   288 a.a.
NCBI ID   WP_011275951.1    Uniprot ID   -
Organism   Staphylococcus haemolyticus strain FDAARGOS_517     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 291185..339513 308985..309851 within 0


Gene organization within MGE regions


Location: 291185..339513
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX85_RS01515 (EGX85_01520) - 293045..294745 (-) 1701 WP_011275937.1 proline--tRNA ligase -
  EGX85_RS01520 (EGX85_01525) rseP 294764..296050 (-) 1287 WP_011275938.1 RIP metalloprotease RseP -
  EGX85_RS01525 (EGX85_01530) - 296261..297043 (-) 783 WP_011275939.1 phosphatidate cytidylyltransferase -
  EGX85_RS01530 (EGX85_01535) - 297047..297817 (-) 771 WP_011275940.1 isoprenyl transferase -
  EGX85_RS01535 (EGX85_01540) frr 298043..298597 (-) 555 WP_011275941.1 ribosome recycling factor -
  EGX85_RS01540 (EGX85_01545) pyrH 298615..299337 (-) 723 WP_011275942.1 UMP kinase -
  EGX85_RS01545 (EGX85_01550) tsf 299474..300352 (-) 879 WP_011275943.1 translation elongation factor Ts -
  EGX85_RS01550 (EGX85_01555) rpsB 300510..301298 (-) 789 WP_011275944.1 30S ribosomal protein S2 -
  EGX85_RS01555 (EGX85_01560) codY 301565..302338 (-) 774 WP_011275945.1 GTP-sensing pleiotropic transcriptional regulator CodY -
  EGX85_RS01560 (EGX85_01565) hslU 302360..303763 (-) 1404 WP_011275946.1 ATP-dependent protease ATPase subunit HslU -
  EGX85_RS01565 (EGX85_01570) hslV 303822..304367 (-) 546 WP_011275947.1 ATP-dependent protease subunit HslV -
  EGX85_RS01570 (EGX85_01575) xerC 304368..305261 (-) 894 WP_011275948.1 tyrosine recombinase XerC -
  EGX85_RS01575 (EGX85_01580) trmFO 305406..306713 (-) 1308 WP_011275949.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  EGX85_RS01580 (EGX85_01585) topA 306737..308806 (-) 2070 WP_011275950.1 type I DNA topoisomerase -
  EGX85_RS01585 (EGX85_01590) dprA 308985..309851 (-) 867 WP_011275951.1 DNA-processing protein DprA Machinery gene
  EGX85_RS01590 (EGX85_01595) - 310070..311299 (-) 1230 WP_011275952.1 aminoacyltransferase -
  EGX85_RS01595 (EGX85_01600) sucD 311599..312504 (-) 906 WP_011275953.1 succinate--CoA ligase subunit alpha -
  EGX85_RS01600 (EGX85_01605) sucC 312526..313692 (-) 1167 WP_011275954.1 ADP-forming succinate--CoA ligase subunit beta -
  EGX85_RS01605 (EGX85_01610) - 313804..314571 (-) 768 WP_011275955.1 ribonuclease HII -
  EGX85_RS01610 (EGX85_01615) ylqF 314555..315439 (-) 885 WP_011275956.1 ribosome biogenesis GTPase YlqF -
  EGX85_RS01615 (EGX85_01620) - 315677..318271 (+) 2595 WP_011275957.1 YfhO family protein -
  EGX85_RS01620 (EGX85_01625) - 318273..320882 (+) 2610 WP_011275958.1 YfhO family protein -
  EGX85_RS01625 (EGX85_01630) rplS 321039..321389 (-) 351 WP_011275959.1 50S ribosomal protein L19 -
  EGX85_RS01630 (EGX85_01635) trmD 321494..322231 (-) 738 WP_011275960.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  EGX85_RS01635 (EGX85_01640) rimM 322231..322734 (-) 504 WP_011275961.1 ribosome maturation factor RimM -
  EGX85_RS01640 (EGX85_01645) rpsP 322853..323128 (-) 276 WP_011275962.1 30S ribosomal protein S16 -
  EGX85_RS01645 (EGX85_01650) ffh 323375..324745 (-) 1371 WP_011275963.1 signal recognition particle protein -
  EGX85_RS01650 (EGX85_01655) - 324771..325103 (-) 333 WP_011275964.1 putative DNA-binding protein -
  EGX85_RS01655 (EGX85_01660) ftsY 325090..326313 (-) 1224 WP_011275965.1 signal recognition particle-docking protein FtsY -
  EGX85_RS01660 (EGX85_01665) smc 326310..329879 (-) 3570 WP_016930692.1 chromosome segregation protein SMC -
  EGX85_RS01665 (EGX85_01670) rnc 329964..330701 (-) 738 WP_011275967.1 ribonuclease III -
  EGX85_RS01670 (EGX85_01675) - 330787..331020 (-) 234 WP_001830184.1 acyl carrier protein -
  EGX85_RS01675 (EGX85_01680) fabG 331133..331870 (-) 738 WP_011275968.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  EGX85_RS01680 (EGX85_01685) fabD 331860..332789 (-) 930 WP_011275969.1 ACP S-malonyltransferase -
  EGX85_RS01685 (EGX85_01690) plsX 332782..333768 (-) 987 WP_011275970.1 phosphate acyltransferase PlsX -
  EGX85_RS01690 (EGX85_01695) fapR 333770..334330 (-) 561 WP_011275971.1 transcription factor FapR -
  EGX85_RS01695 (EGX85_01700) recG 334466..336517 (-) 2052 WP_016930693.1 ATP-dependent DNA helicase RecG -
  EGX85_RS01700 (EGX85_01705) - 336672..337472 (-) 801 WP_011275973.1 thermonuclease family protein -
  EGX85_RS01705 (EGX85_01710) fakA 337658..339316 (-) 1659 WP_011275974.1 fatty acid kinase catalytic subunit FakA -

Sequence

Protein


Download         Length: 288 a.a.        Molecular weight: 33058.12 Da        Isoelectric Point: 9.4081

>NTDB_id=325984 EGX85_RS01585 WP_011275951.1 308985..309851(-) (dprA) [Staphylococcus haemolyticus strain FDAARGOS_517]
MTNNNILLLKLIWLGYTTQHIHHLLKLNPEFFKFSYTDQIDSIKNWDKLFHKGDFIDRYNHLNDKEILSFLNQHKISFVT
PFNANYPRLLKEIYDYPFVLFYQGDPQLLTSPNTLGVVGSRNATEYSAKAMQYLFPKFKQIPLTIISGLAKGADSIAHHF
AIEYQLPTIAVLGFGHMMHYPRETQKLRNIIEVKGLVISEYPPFTSVRRYHFPQRNRLISGLSQGVLITEASVRSGSQIT
IDCALDQNRNIYVLPGSIFNPLTKGNLKRAQEGAMIVTSADDILCDYK

Nucleotide


Download         Length: 867 bp        

>NTDB_id=325984 EGX85_RS01585 WP_011275951.1 308985..309851(-) (dprA) [Staphylococcus haemolyticus strain FDAARGOS_517]
ATGACTAACAACAACATATTACTTTTGAAATTAATTTGGTTAGGTTATACGACCCAACATATTCATCATTTATTAAAATT
AAATCCTGAATTTTTTAAATTCTCTTATACTGATCAAATAGATTCAATAAAAAATTGGGACAAGTTATTTCATAAAGGTG
ATTTTATTGATAGATATAATCATTTAAATGATAAAGAAATTTTGTCATTTTTGAATCAACACAAGATAAGTTTTGTAACA
CCGTTTAACGCTAATTATCCTCGACTATTAAAAGAAATTTATGATTATCCGTTTGTCCTATTTTACCAAGGTGACCCCCA
ATTATTAACATCCCCCAATACATTAGGTGTGGTGGGCTCAAGAAATGCAACAGAGTACTCAGCTAAAGCCATGCAATACT
TATTTCCTAAATTTAAACAAATTCCACTAACCATTATTTCCGGTTTGGCAAAAGGTGCTGATAGCATTGCACATCATTTT
GCTATAGAGTATCAATTACCTACTATAGCTGTTTTAGGTTTTGGTCATATGATGCATTACCCTAGAGAAACGCAAAAATT
ACGCAACATAATTGAAGTAAAAGGTTTAGTTATTAGTGAATATCCGCCATTCACTAGTGTTAGGCGATATCACTTTCCGC
AACGCAATCGTTTGATAAGCGGTCTTTCACAAGGGGTTTTAATAACTGAAGCAAGTGTTAGAAGCGGTAGTCAAATTACA
ATTGATTGCGCATTAGACCAAAATAGAAATATATATGTATTACCAGGTTCAATATTTAATCCACTAACTAAAGGTAATTT
GAAACGAGCTCAAGAAGGTGCGATGATTGTAACCTCAGCTGATGATATTCTATGTGATTATAAATAG

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-278)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus MW2

49.825

98.958

0.493
  dprA Staphylococcus aureus N315

49.825

98.958

0.493
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

36.395

100

0.372
  dprA/cilB/dalA Streptococcus pneumoniae D39

36.395

100

0.372
  dprA/cilB/dalA Streptococcus pneumoniae R6

36.395

100

0.372
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

36.395

100

0.372
  dprA Streptococcus mutans UA159

37.544

98.958

0.372
  dprA/cilB/dalA Streptococcus mitis SK321

35.374

100

0.361
  dprA Legionella pneumophila strain ERS1305867

42.105

85.764

0.361

Multiple sequence alignment