Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   SMUNN2025_RS08510 Genome accession   NC_013928
Coordinates   1759003..1759899 (-) Length   298 a.a.
NCBI ID   WP_012997936.1    Uniprot ID   -
Organism   Streptococcus mutans NN2025     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1754003..1764899
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNN2025_RS08510 (SmuNN2025_1661) comR 1759003..1759899 (-) 897 WP_012997936.1 helix-turn-helix domain-containing protein Regulator
  SMUNN2025_RS08515 (SmuNN2025_1662) - 1760098..1760661 (-) 564 WP_002267382.1 hypothetical protein -
  SMUNN2025_RS08520 (SmuNN2025_1663) tadA 1760658..1761128 (-) 471 WP_002276391.1 tRNA adenosine(34) deaminase TadA -
  SMUNN2025_RS08525 (SmuNN2025_1664) - 1761128..1761904 (-) 777 WP_002264123.1 MBL fold metallo-hydrolase -
  SMUNN2025_RS08530 (SmuNN2025_1665) - 1761981..1762994 (-) 1014 WP_002262915.1 YdcF family protein -
  SMUNN2025_RS08535 (SmuNN2025_1666) - 1763421..1763984 (-) 564 WP_012997937.1 nucleotidyltransferase family protein -

Sequence

Protein


Download         Length: 298 a.a.        Molecular weight: 34734.86 Da        Isoelectric Point: 4.5183

>NTDB_id=32453 SMUNN2025_RS08510 WP_012997936.1 1759003..1759899(-) (comR) [Streptococcus mutans NN2025]
MSIKETIGKKIREVREEKGLSREQLCDTEEELTVRQLVRIELGQSLPSIVKLEYIAKVLETDLGTLLAGESFTIPEEYFT
MKYQLFKFPSYGDSERLAQKTQMIEDIYEKYFDVLTEEELFTLELLDNSLDYISTRKTAAAEDIFEDFFKQLLTKKHYSF
NDLLLAKYYAIQCQDKDYKEITLQILETTILQQDVSGDEYYNIELLGVLTAIAGVYLDHGLYYKLKALVVKMDDIISKTQ
QYSIKPGLLMFEAKYYLYAEYDKKKAKECYDLAALLAQNFGDKVLEANIFSERKKDQL

Nucleotide


Download         Length: 897 bp        

>NTDB_id=32453 SMUNN2025_RS08510 WP_012997936.1 1759003..1759899(-) (comR) [Streptococcus mutans NN2025]
ATGAGCATAAAAGAAACAATTGGGAAAAAGATTAGGGAAGTTCGTGAGGAAAAGGGTTTATCACGTGAACAATTGTGTGA
CACTGAAGAAGAACTAACAGTTCGCCAGTTGGTACGTATCGAGCTAGGACAGTCTTTACCCTCTATTGTAAAATTGGAAT
ACATTGCAAAAGTATTAGAAACTGATTTAGGAACTTTACTTGCAGGTGAAAGTTTTACTATACCAGAAGAGTATTTCACT
ATGAAGTATCAACTTTTCAAATTTCCCAGTTATGGTGATTCTGAACGCTTAGCTCAAAAAACGCAAATGATTGAAGATAT
TTATGAAAAGTATTTTGATGTTTTGACGGAGGAGGAACTTTTTACTTTAGAATTACTAGATAACTCTCTAGATTATATTT
CAACAAGAAAAACGGCAGCAGCAGAAGATATCTTTGAAGATTTTTTTAAACAACTTTTAACAAAAAAACATTATTCTTTC
AATGATTTATTATTGGCAAAGTACTATGCTATTCAATGTCAGGATAAAGATTATAAGGAAATAACCTTGCAGATACTCGA
AACGACTATTTTACAGCAAGATGTCTCAGGTGATGAGTATTACAATATTGAACTTTTAGGAGTGTTGACAGCTATAGCAG
GAGTTTATTTAGATCATGGTTTATATTATAAATTAAAGGCTTTGGTCGTTAAAATGGATGATATCATCTCTAAAACGCAA
CAATATAGTATTAAACCTGGATTATTAATGTTTGAAGCAAAATATTATCTCTATGCTGAATATGATAAAAAGAAAGCAAA
GGAATGTTATGATTTAGCTGCTTTACTAGCACAGAATTTTGGAGATAAAGTTTTAGAAGCTAATATCTTTTCTGAAAGAA
AAAAGGATCAGCTTTAA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(75-292)

Helix-turn-helix (HTH_3)

(11-64)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus salivarius SK126

42.14

100

0.423
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

42.088

99.664

0.419
  comR Streptococcus thermophilus LMG 18311

41.472

100

0.416
  comR Streptococcus salivarius strain HSISS4

41.472

100

0.416
  comR Streptococcus thermophilus LMD-9

41.137

100

0.413
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

40.404

99.664

0.403

Multiple sequence alignment