Detailed information NTG0324483

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: EGC57_RS04715
• Genome accession: NZ_CP033621
• Coordinates: 897117..897953 (+)
• Length: 278 a.a.
• NCBI ID: WP_076639652.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain M75
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 892117..902953

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGC57_RS04685 (EGC57_04695)	-	892599..893039 (+)	441	WP_009880949.1	hypothetical protein	-
EGC57_RS04690 (EGC57_04700)	-	893089..894000 (-)	912	WP_076639650.1	diacylglycerol kinase family protein	-
EGC57_RS04695 (EGC57_04705)	-	894117..894767 (-)	651	WP_002984629.1	hemolysin III family protein	-
EGC57_RS04700 (EGC57_04710)	-	894764..895204 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
EGC57_RS04705 (EGC57_04715)	ylqF	895423..896271 (+)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
EGC57_RS04710 (EGC57_04720)	-	896261..897052 (+)	792	WP_076639651.1	ribonuclease HII	-
EGC57_RS04715 (EGC57_04725)	dprA	897117..897953 (+)	837	WP_076639652.1	DNA-processing protein DprA	Machinery gene
EGC57_RS04720 (EGC57_04730)	topA	898060..900189 (+)	2130	WP_076639653.1	type I DNA topoisomerase	-
EGC57_RS09555	-	900264..901148 (-)	885	Protein_861	LysR family transcriptional regulator	-
EGC57_RS04735 (EGC57_04745)	-	901161..901727 (+)	567	Protein_862	PTS sugar transporter subunit IIC	-
EGC57_RS04740 (EGC57_04750)	-	901742..902694 (+)	953	Protein_863	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30978.99 Da
• Isoelectric Point: 9.2511

>NTDB_id=324483 EGC57_RS04715 WP_076639652.1 897117..897953(+) (dprA) [Streptococcus pyogenes strain M75]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=324483 EGC57_RS04715 WP_076639652.1 897117..897953(+) (dprA) [Streptococcus pyogenes strain M75]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGCTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCACCT
TGTGATAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363