Detailed information NTG0323021

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: EB818_RS04550
• Genome accession: NZ_CP033335
• Coordinates: 871439..872275 (+)
• Length: 278 a.a.
• NCBI ID: WP_020905195.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY208
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 866439..877275

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EB818_RS04520 (EB818_04530)	-	866987..867361 (+)	375	WP_011054498.1	hypothetical protein	-
EB818_RS04525 (EB818_04535)	-	867411..868322 (-)	912	WP_002984631.1	diacylglycerol kinase family protein	-
EB818_RS04530 (EB818_04540)	-	868439..869089 (-)	651	WP_002984629.1	hemolysin III family protein	-
EB818_RS04535 (EB818_04545)	-	869086..869526 (-)	441	WP_002984627.1	DUF1836 domain-containing protein	-
EB818_RS04540 (EB818_04550)	ylqF	869745..870593 (+)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
EB818_RS04545 (EB818_04555)	-	870583..871374 (+)	792	WP_129322691.1	ribonuclease HII	-
EB818_RS04550 (EB818_04560)	dprA	871439..872275 (+)	837	WP_020905195.1	DNA-processing protein DprA	Machinery gene
EB818_RS04555 (EB818_04565)	topA	872382..874511 (+)	2130	WP_011017773.1	type I DNA topoisomerase	-
EB818_RS09145	-	874586..875470 (-)	885	Protein_820	LysR family transcriptional regulator	-
EB818_RS04570 (EB818_04580)	-	875483..876049 (+)	567	Protein_821	PTS sugar transporter subunit IIC	-
EB818_RS04575 (EB818_04585)	-	876064..877016 (+)	953	Protein_822	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30988.00 Da
• Isoelectric Point: 9.2514

>NTDB_id=323021 EB818_RS04550 WP_020905195.1 871439..872275(+) (dprA) [Streptococcus pyogenes strain TSPY208]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=323021 EB818_RS04550 WP_020905195.1 871439..872275(+) (dprA) [Streptococcus pyogenes strain TSPY208]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367