Detailed information NTG0318326

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: D8S77_RS04925
• Genome accession: NZ_CP032700
• Coordinates: 955777..956613 (-)
• Length: 278 a.a.
• NCBI ID: WP_111693218.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY556
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 950777..961613

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D8S77_RS04900 (D8S77_04905)	-	950911..951903 (-)	993	Protein_889	D-lactate dehydrogenase	-
D8S77_RS04905 (D8S77_04910)	-	951918..952484 (-)	567	Protein_890	PTS sugar transporter subunit IIC	-
D8S77_RS09285	-	952524..953465 (+)	942	Protein_891	LysR family transcriptional regulator	-
D8S77_RS04920 (D8S77_04925)	topA	953541..955670 (-)	2130	WP_115354118.1	type I DNA topoisomerase	-
D8S77_RS04925 (D8S77_04930)	dprA	955777..956613 (-)	837	WP_111693218.1	DNA-processing protein DprA	Machinery gene
D8S77_RS04930 (D8S77_04935)	-	956678..957469 (-)	792	WP_011285534.1	ribonuclease HII	-
D8S77_RS04935 (D8S77_04940)	ylqF	957459..958307 (-)	849	WP_129321912.1	ribosome biogenesis GTPase YlqF	-
D8S77_RS04940 (D8S77_04945)	-	958526..958966 (+)	441	WP_002989774.1	DUF1836 domain-containing protein	-
D8S77_RS04945 (D8S77_04950)	trhA	958963..959613 (+)	651	WP_129321914.1	PAQR family membrane homeostasis protein TrhA	-
D8S77_RS04950 (D8S77_04955)	-	959730..960641 (+)	912	WP_002989777.1	diacylglycerol/lipid kinase family protein	-
D8S77_RS04955 (D8S77_04960)	-	960691..961059 (-)	369	WP_010922310.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31073.07 Da
• Isoelectric Point: 9.2565

>NTDB_id=318326 D8S77_RS04925 WP_111693218.1 955777..956613(-) (dprA) [Streptococcus pyogenes strain TSPY556]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=318326 D8S77_RS04925 WP_111693218.1 955777..956613(-) (dprA) [Streptococcus pyogenes strain TSPY556]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAAGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	56.835	100	0.568
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367