Detailed information NTG0318270

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: D8S76_RS04830
• Genome accession: NZ_CP032699
• Coordinates: 923912..924748 (+)
• Length: 278 a.a.
• NCBI ID: WP_023079425.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY155
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 918912..929748

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D8S76_RS04800 (D8S76_04795)	-	919400..919834 (+)	435	WP_023079442.1	hypothetical protein	-
D8S76_RS04805 (D8S76_04800)	-	919884..920795 (-)	912	WP_023079407.1	diacylglycerol kinase family protein	-
D8S76_RS04810 (D8S76_04805)	-	920912..921562 (-)	651	WP_023079408.1	hemolysin III family protein	-
D8S76_RS04815 (D8S76_04810)	-	921559..921999 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
D8S76_RS04820 (D8S76_04815)	ylqF	922218..923066 (+)	849	WP_023612970.1	ribosome biogenesis GTPase YlqF	-
D8S76_RS04825 (D8S76_04820)	-	923056..923847 (+)	792	WP_023079417.1	ribonuclease HII	-
D8S76_RS04830 (D8S76_04825)	dprA	923912..924748 (+)	837	WP_023079425.1	DNA-processing protein DprA	Machinery gene
D8S76_RS04835 (D8S76_04830)	topA	924855..926984 (+)	2130	WP_011017773.1	type I DNA topoisomerase	-
D8S76_RS09600	-	927059..927943 (-)	885	Protein_891	LysR family transcriptional regulator	-
D8S76_RS04850 (D8S76_04845)	-	927956..928509 (+)	554	Protein_892	PTS sugar transporter subunit IIC	-
D8S76_RS04855 (D8S76_04850)	-	928524..929516 (+)	993	WP_023078604.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31046.98 Da
• Isoelectric Point: 8.5827

>NTDB_id=318270 D8S76_RS04830 WP_023079425.1 923912..924748(+) (dprA) [Streptococcus pyogenes strain TSPY155]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEDR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=318270 D8S76_RS04830 WP_023079425.1 923912..924748(+) (dprA) [Streptococcus pyogenes strain TSPY155]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCTGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACTGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGACCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367