Detailed information NTG0317813

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: MGAS28085_RS04905
• Genome accession: NZ_CP032666
• Coordinates: 956230..957066 (-)
• Length: 278 a.a.
• NCBI ID: WP_002995009.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS28085
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 951230..962066

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS28085_RS04880 (MGAS28085_04880)	-	951470..952462 (-)	993	WP_021340798.1	D-lactate dehydrogenase	-
MGAS28085_RS04885 (MGAS28085_04885)	-	952477..953022 (-)	546	Protein_894	PTS sugar transporter subunit IIC	-
MGAS28085_RS09415	-	953062..953919 (+)	858	Protein_895	LysR family transcriptional regulator	-
MGAS28085_RS04900 (MGAS28085_04900)	topA	953994..956123 (-)	2130	WP_011284793.1	type I DNA topoisomerase	-
MGAS28085_RS04905 (MGAS28085_04905)	dprA	956230..957066 (-)	837	WP_002995009.1	DNA-processing protein DprA	Machinery gene
MGAS28085_RS04910 (MGAS28085_04910)	-	957131..957922 (-)	792	WP_011888871.1	ribonuclease HII	-
MGAS28085_RS04915 (MGAS28085_04915)	ylqF	957912..958760 (-)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
MGAS28085_RS04920 (MGAS28085_04920)	-	958979..959419 (+)	441	WP_002984627.1	DUF1836 domain-containing protein	-
MGAS28085_RS04925 (MGAS28085_04925)	-	959416..960066 (+)	651	WP_002984629.1	hemolysin III family protein	-
MGAS28085_RS04930 (MGAS28085_04930)	-	960183..961094 (+)	912	WP_127821083.1	diacylglycerol kinase family protein	-
MGAS28085_RS04935 (MGAS28085_04935)	-	961144..961578 (-)	435	WP_021340932.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30970.91 Da
• Isoelectric Point: 8.8230

>NTDB_id=317813 MGAS28085_RS04905 WP_002995009.1 956230..957066(-) (dprA) [Streptococcus pyogenes strain MGAS28085]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=317813 MGAS28085_RS04905 WP_002995009.1 956230..957066(-) (dprA) [Streptococcus pyogenes strain MGAS28085]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367