Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   D7I46_RS08985 Genome accession   NZ_CP032627
Coordinates   1930225..1931448 (+) Length   407 a.a.
NCBI ID   WP_120772596.1    Uniprot ID   A0A387BGF1
Organism   Lactococcus allomyrinae strain 1JSPR-7     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1925225..1936448
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7I46_RS08955 (D7I46_08955) yajC 1925612..1925941 (-) 330 WP_120772590.1 preprotein translocase subunit YajC -
  D7I46_RS08960 (D7I46_08960) - 1926227..1926895 (-) 669 WP_120772591.1 DNA alkylation repair protein -
  D7I46_RS08965 (D7I46_08965) - 1926895..1927287 (-) 393 WP_120772592.1 tautomerase family protein -
  D7I46_RS08970 (D7I46_08970) - 1927674..1928423 (-) 750 WP_120772593.1 ABC transporter permease -
  D7I46_RS08975 (D7I46_08975) - 1928432..1929295 (-) 864 WP_120772594.1 ATP-binding cassette domain-containing protein -
  D7I46_RS08980 (D7I46_08980) rlmH 1929386..1929865 (-) 480 WP_120772595.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  D7I46_RS08985 (D7I46_08985) htrA 1930225..1931448 (+) 1224 WP_120772596.1 S1C family serine protease Regulator
  D7I46_RS08990 (D7I46_08990) - 1931573..1932571 (+) 999 WP_120772597.1 glycosyltransferase family 4 protein -
  D7I46_RS08995 (D7I46_08995) - 1932889..1934229 (+) 1341 WP_120772598.1 glycosyltransferase family 4 protein -
  D7I46_RS09000 (D7I46_09000) - 1934384..1934608 (+) 225 WP_120772599.1 YkuJ family protein -
  D7I46_RS13520 - 1934826..1935143 (+) 318 WP_240424390.1 hypothetical protein -
  D7I46_RS09005 (D7I46_09005) - 1935152..1935829 (+) 678 WP_240424392.1 hypothetical protein -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 41857.40 Da        Isoelectric Point: 4.5475

>NTDB_id=317320 D7I46_RS08985 WP_120772596.1 1930225..1931448(+) (htrA) [Lactococcus allomyrinae strain 1JSPR-7]
MSKGNFGKMLLTGVVGGAIALGGSAIYQNTTNNNATSTSGSSVPVKTVKVDVNTDTTAAIKKVSNAVVSVLNYQNQSSSD
DVFNSIFGQNSGNSQSSATSSLASEGSGVIYKKEDGKAYIVTNNHVVEGANSLEVLLAGGQKVKATLVGTDAYTDLAVLK
IDDNDVKEVATFADSSNLTIGEPAIAVGSPLGSEFANTATEGIVSAINRQVSMQNDEGQNVNVNAIQTDAAINPGNSGGA
LINIEGQVIGITQSKLTTTQDGSTSVEGMGFAIPSNDVVNIIAKLEKDGKVIRPALGITMVDLSQFSTDDLNQLKLPDSV
TGGVVVHTVQSGMPASTAGLKAGDVITKIGDTTITSSTDLQSALYKYNIGDTVAITYYRDGKSHTANVKLNKSTSDLQQS
SSSSQNP

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=317320 D7I46_RS08985 WP_120772596.1 1930225..1931448(+) (htrA) [Lactococcus allomyrinae strain 1JSPR-7]
ATGTCAAAAGGTAATTTCGGGAAAATGCTCTTGACTGGTGTCGTAGGTGGGGCCATCGCACTAGGTGGGAGTGCAATTTA
CCAAAACACAACAAACAATAACGCCACTAGTACTAGTGGTTCTTCCGTTCCAGTCAAGACTGTAAAAGTTGATGTTAATA
CAGACACAACTGCTGCAATCAAAAAAGTTTCTAATGCGGTTGTTTCCGTCCTTAACTATCAAAATCAGAGTTCTAGTGAT
GACGTTTTCAACAGTATCTTCGGACAAAATAGTGGAAACAGCCAAAGTTCTGCAACTTCTAGTTTAGCAAGTGAAGGTTC
TGGAGTCATTTACAAAAAAGAAGATGGTAAAGCTTATATCGTTACTAACAATCACGTTGTAGAAGGTGCTAATAGCCTCG
AAGTTCTGTTAGCTGGTGGTCAGAAAGTAAAAGCTACTCTAGTTGGCACGGATGCTTATACTGACCTTGCCGTACTTAAA
ATTGATGATAATGACGTTAAAGAGGTAGCTACTTTCGCAGATTCTAGTAACTTAACAATTGGAGAACCTGCCATTGCAGT
CGGCTCTCCTCTCGGTTCTGAGTTTGCTAATACCGCAACTGAAGGAATTGTTTCAGCCATTAATCGTCAAGTTTCAATGC
AAAATGATGAAGGACAAAATGTCAATGTCAATGCAATTCAAACTGATGCCGCCATCAATCCGGGAAATTCTGGAGGAGCG
TTAATTAATATTGAAGGGCAAGTCATTGGTATTACACAGTCAAAACTGACTACTACCCAAGATGGCTCAACAAGCGTTGA
AGGAATGGGATTTGCCATTCCATCTAATGATGTGGTTAATATTATTGCTAAACTTGAAAAAGACGGTAAAGTTATTCGTC
CTGCATTAGGTATTACAATGGTTGATTTGTCACAATTTTCAACTGACGATCTCAACCAGCTCAAACTTCCTGATAGTGTA
ACTGGTGGTGTGGTTGTCCATACTGTTCAATCAGGTATGCCTGCTAGCACTGCGGGTCTAAAAGCTGGTGATGTTATCAC
AAAGATTGGCGATACAACAATTACCTCTTCAACAGATTTACAAAGCGCTCTTTATAAATATAATATTGGAGATACTGTCG
CTATCACTTATTACCGTGATGGTAAATCTCACACAGCTAATGTTAAACTCAATAAATCAACAAGTGACTTGCAACAATCA
AGCTCATCAAGCCAAAATCCTTAG

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(106-251)

Peptidase family M50 (Peptidase_M50)

(253-395)

PDZ domain (PDZ_2)

(294-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A387BGF1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

54.082

96.314

0.521
  htrA Streptococcus mitis NCTC 12261

54.617

93.12

0.509
  htrA Streptococcus pneumoniae Rx1

58.017

84.275

0.489
  htrA Streptococcus pneumoniae D39

58.017

84.275

0.489
  htrA Streptococcus pneumoniae R6

58.017

84.275

0.489
  htrA Streptococcus pneumoniae TIGR4

58.017

84.275

0.489
  htrA Streptococcus mutans UA159

49.123

98.034

0.482

Multiple sequence alignment