Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   D7D53_RS08845 Genome accession   NZ_CP032621
Coordinates   1755039..1756388 (-) Length   449 a.a.
NCBI ID   WP_120770735.1    Uniprot ID   A0A387AZE3
Organism   Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1750039..1761388
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7D53_RS08830 (D7D53_08830) - 1750235..1753960 (-) 3726 WP_120770734.1 phosphoribosylformylglycinamidine synthase -
  D7D53_RS10320 (D7D53_08835) - 1754016..1754159 (-) 144 WP_120770879.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  D7D53_RS08840 (D7D53_08840) purC 1754161..1754868 (-) 708 WP_000043282.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  D7D53_RS08845 (D7D53_08845) comB 1755039..1756388 (-) 1350 WP_120770735.1 competence pheromone export protein ComB Regulator
  D7D53_RS08850 (D7D53_08850) comA 1756401..1758554 (-) 2154 WP_120770736.1 peptide cleavage/export ABC transporter ComA Regulator
  D7D53_RS08855 (D7D53_08855) - 1758987..1759166 (-) 180 WP_050219186.1 hypothetical protein -
  D7D53_RS10250 (D7D53_08860) - 1759247..1759450 (-) 204 WP_120770737.1 bacteriocin immunity protein -
  D7D53_RS08865 (D7D53_08865) - 1759454..1759621 (-) 168 WP_001047583.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  D7D53_RS08875 (D7D53_08875) - 1760117..1760296 (-) 180 WP_120770739.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  D7D53_RS08885 (D7D53_08885) - 1760505..1760693 (-) 189 WP_120770741.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  D7D53_RS08890 (D7D53_08890) - 1761137..1761373 (-) 237 WP_000136444.1 acyl carrier protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49874.88 Da        Isoelectric Point: 5.7895

>NTDB_id=317221 D7D53_RS08845 WP_120770735.1 1755039..1756388(-) (comB) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
MKPEFLESAEFYNRRYHNFSSRVIVPMSLLLVFLLGFATFAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGELLVQYQEGAEGVQAEAYASQLDMLKDQKKQLEYLQKSLQEGENHFPKEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLASQNLAYSLYQSYKSQGEENPQAKAQVMAQVEAQLS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLDQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSTMVAEGTLLAQLYPSLEKEGKAKLTAYLSSKDVARINIGDSIRYTTTHDAKNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=317221 D7D53_RS08845 WP_120770735.1 1755039..1756388(-) (comB) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTGTCCCCAT
GTCCCTTCTGCTTGTGTTTTTGCTTGGCTTTGCAACTTTTGCAGAGAAGGAGATGAGTTTGTCTACTAGAGCTACTGTCG
AGCCTAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGCATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGAGCTTCTTGTTCAATACCAGGAAGGGGCGGAAGGTGTCCAAGCAGAGGCCTATGCTAGTCAGTTGGA
CATGCTCAAGGATCAAAAAAAGCAATTGGAGTATTTGCAGAAGAGCCTGCAAGAAGGGGAGAATCACTTTCCAAAGGAGG
ATAAATTTGGCTATCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGTCAAACCCAAGCCGAAATCGGCAACCTCATCAGCCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTGCTTCCTTGGCCAGTCAGAATCTAGCCTACTCTCTCT
ACCAGTCCTACAAATCTCAGGGTGAGGAAAATCCGCAAGCTAAGGCTCAGGTAATGGCGCAGGTTGAAGCGCAGCTTTCT
CAGTTAGAATCCAGTCTTGCTACTTACCGTGTTCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGCTTAAG
CAGTCAATTGGAGTCTCTCAAATCCCAACACTTGGCAAAGGTTGGTCAAGAATTGACCCTTCTAGACCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACAGCGAGTGAGGATGGGGTACTTCAT
CTTAATCCTGAGACCAGTGATTCTACCATGGTTGCAGAGGGAACCCTACTAGCCCAACTCTATCCATCCTTGGAAAAAGA
AGGGAAAGCCAAACTAACAGCTTATCTTAGTTCAAAGGATGTAGCAAGGATCAATATCGGTGATTCTATTCGCTATACTA
CGACTCATGATGCCAAGAATCAACTTTTCCTAGATTCTACTATTACAAGTATTGATGCGACAGCGACTAAGACTGAGAAA
GGGAATTTCTTTAAAATTGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTCGATATGGGGTGGAAGGTCG
CCTGCAGATGATTACGGGCAAGAAAAGTTATCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A387AZE3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

96.882

100

0.969
  comB Streptococcus pneumoniae Rx1

95.323

100

0.953
  comB Streptococcus pneumoniae D39

95.323

100

0.953
  comB Streptococcus pneumoniae R6

95.323

100

0.953
  comB Streptococcus mitis NCTC 12261

95.323

100

0.953
  comB Streptococcus pneumoniae TIGR4

95.1

100

0.951
  comB Streptococcus gordonii str. Challis substr. CH1

55.333

100

0.555

Multiple sequence alignment