Detailed information NTG0317199

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: D7D53_RS07065
• Genome accession: NZ_CP032621
• Coordinates: 1417018..1419171 (+)
• Length: 717 a.a.
• NCBI ID: WP_120770556.1
• Uniprot ID: -
• Organism: Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1412018..1424171

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D7D53_RS07030 (D7D53_07030)	-	1412665..1412964 (-)	300	WP_120770551.1	hypothetical protein	-
D7D53_RS07040 (D7D53_07040)	-	1413561..1413770 (-)	210	WP_033684778.1	Blp family class II bacteriocin	-
D7D53_RS07045 (D7D53_07045)	-	1413786..1414034 (-)	249	WP_120770553.1	Blp family class II bacteriocin	-
D7D53_RS07050 (D7D53_07050)	-	1414280..1415317 (-)	1038	WP_120770554.1	thioredoxin domain-containing protein	-
D7D53_RS10365	-	1415533..1415612 (-)	80	Protein_1340	immunity protein	-
D7D53_RS07055 (D7D53_07055)	-	1415673..1416341 (-)	669	WP_120770555.1	CPBP family intramembrane glutamic endopeptidase	-
D7D53_RS10010	-	1416375..1416542 (-)	168	WP_162927887.1	hypothetical protein	-
D7D53_RS10285	-	1416555..1416734 (-)	180	WP_281268597.1	bacteriocin class II family protein	-
D7D53_RS07065 (D7D53_07065)	comA/nlmT	1417018..1419171 (+)	2154	WP_120770556.1	peptide cleavage/export ABC transporter BlpA	Regulator
D7D53_RS07070 (D7D53_07070)	-	1419182..1420543 (+)	1362	WP_120770557.1	bacteriocin secretion accessory protein	-
D7D53_RS07075 (D7D53_07075)	blpC	1420600..1420755 (+)	156	WP_050390357.1	quorum-sensing system pheromone BlpC	-
D7D53_RS07080 (D7D53_07080)	-	1420798..1422138 (-)	1341	WP_120770558.1	sensor histidine kinase	-
D7D53_RS07085 (D7D53_07085)	comE/blpR	1422152..1422889 (-)	738	WP_120770559.1	response regulator transcription factor	Regulator
D7D53_RS07090 (D7D53_07090)	-	1422894..1423232 (-)	339	WP_120770560.1	LytTR family DNA-binding domain-containing protein	-
D7D53_RS07095 (D7D53_07095)	-	1423509..1423838 (+)	330	WP_049510125.1	hypothetical protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80662.79 Da
• Isoelectric Point: 8.7944

>NTDB_id=317199 D7D53_RS07065 WP_120770556.1 1417018..1419171(+) (comA/nlmT) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAANKMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMGFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMF
IIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKL
VLNILILWFGAQLVMSSKISIGQLITFNTLLSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQTPENPVHSHFL
MGDIEFDDLSYKYGFGRDTLTGINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHI
NYLPQQAYIFNGSILENLTLGGNHMISQEDILKACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKSP
VLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 2154 bp

>NTDB_id=317199 D7D53_RS07065 WP_120770556.1 1417018..1419171(+) (comA/nlmT) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCTAGAGACTGCGGTGTTGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCAAATAAAATGGGATTTGAAACCAGACCTGTTCAAGCAGATAAAACTCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGCGATCCCGACCCTTCTGTAAAAATCACCAAAATGTCAAAAGAACGCTTTTTCTCTGAATGGACTGGAG
TAGCTATTTTTCTAGCTCCCAAACCTAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCTTCCTTCCTCTG
ATTTTCAAACAAAAATCTCTTATTGCTTATATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATCGGTGGTTCTTA
TTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTA
TTACCTATATCCTCCAACAAGTCATGGGCTTCTCCAGAGATTATCTCCTAACTGTTCTGAGTCAGAGATTAAGTATTGAT
GTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCTATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTC
ACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGA
TTCTTGTAGGAGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACATGTTC
ATCATCTTTTCTTTTATGAAGCCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCAT
TATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTGACGAGTGAAGAAAATCGCTATCAAAATATAGACAGTGAAT
TTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAGTATTCTATTTTACAAACGAGTTTAAAACAGGGAACAAAATTA
GTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTT
TAATACACTTCTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCG
CTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAGTTCCAAACCCCAGAAAACCCTGTTCATTCACATTTTTTG
ATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACTTTAACAGGTATTAATCTCACGAT
TAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCT
TTGAACCTTACAAAGGACATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATT
AATTACCTTCCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACTTTGGGCGGTAATCATATGATTAG
CCAAGAAGATATTCTAAAAGCTTGCGAATTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGTTATCAAACTC
AGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCTCCT
GTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCTAAC
TGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGGGGA
AAATCATTGAAGTTGGTAGCCACCAAGAGTTAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (500-649)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (169-438)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	71.888	99.721	0.717
comA	Streptococcus mitis NCTC 12261	66.059	99.442	0.657
comA	Streptococcus gordonii str. Challis substr. CH1	65.042	100	0.651
comA	Streptococcus pneumoniae D39	65.498	99.442	0.651
comA	Streptococcus pneumoniae R6	65.498	99.442	0.651
comA	Streptococcus mitis SK321	65.498	99.442	0.651
comA	Streptococcus pneumoniae Rx1	65.498	99.442	0.651
comA	Streptococcus pneumoniae TIGR4	65.217	99.442	0.649