Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   D7D53_RS07085 Genome accession   NZ_CP032621
Coordinates   1422152..1422889 (-) Length   245 a.a.
NCBI ID   WP_120770559.1    Uniprot ID   -
Organism   Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1417152..1427889
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7D53_RS07070 (D7D53_07070) - 1419182..1420543 (+) 1362 WP_120770557.1 bacteriocin secretion accessory protein -
  D7D53_RS07075 (D7D53_07075) blpC 1420600..1420755 (+) 156 WP_050390357.1 quorum-sensing system pheromone BlpC -
  D7D53_RS07080 (D7D53_07080) - 1420798..1422138 (-) 1341 WP_120770558.1 sensor histidine kinase -
  D7D53_RS07085 (D7D53_07085) comE/blpR 1422152..1422889 (-) 738 WP_120770559.1 response regulator transcription factor Regulator
  D7D53_RS07090 (D7D53_07090) - 1422894..1423232 (-) 339 WP_120770560.1 LytTR family DNA-binding domain-containing protein -
  D7D53_RS07095 (D7D53_07095) - 1423509..1423838 (+) 330 WP_049510125.1 hypothetical protein -
  D7D53_RS07100 (D7D53_07100) - 1423901..1424950 (-) 1050 WP_120770561.1 ABC transporter permease -
  D7D53_RS07105 (D7D53_07105) pptA 1424947..1425678 (-) 732 WP_120770562.1 ABC transporter ATP-binding protein Regulator
  D7D53_RS07110 (D7D53_07110) - 1425746..1426156 (+) 411 WP_120770563.1 HIT family protein -
  D7D53_RS07115 (D7D53_07115) - 1426166..1426453 (+) 288 WP_120770564.1 hypothetical protein -
  D7D53_RS07120 (D7D53_07120) dnaJ 1426479..1427615 (-) 1137 WP_120770565.1 molecular chaperone DnaJ -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28852.01 Da        Isoelectric Point: 6.4147

>NTDB_id=317200 D7D53_RS07085 WP_120770559.1 1422152..1422889(-) (comE/blpR) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSPRAHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFPNGRSCLIARYKVREVSEA
INNLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=317200 D7D53_RS07085 WP_120770559.1 1422152..1422889(-) (comE/blpR) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
ATGAGAATATTTGTTTTAGAAGATGATTTTTCCCAACAGACTAGGATTGAAACGACGATTGAGAAACTCTTGAAAGAACA
TCATATCACTCCCAGTTCTTTTGAAGTCTTTGGTAAGCCAGACCAGCTACTGGCAGAGGTGCATGAGAAGGGTGCACATC
AGCTGTTCTTTTTGGACATTGAGATTCGAAATGAAGAGATGAAGGGGCTGGAAGTAGCTAGAAAAATTCGGGATCGAGAT
CCTTATGCCCTGATTGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTGTCCTTTCGTTACCAAGTGTCTGCTTTGGA
CTACATTGATAAGGCCCTTTCGGCAGAGGAATTTGAATCTCGGATTGAGACAGCCCTCCTTTATGCCAATAGTCAAGACA
GTAAAAGTCTGGCGGAAGATTGTTTTTACTTTAAATCAAAATTTGCTCAATTTCAGTATCCTTTTAAAGAGGTTTACTAT
CTCGAAACGTCGCCCAGAGCCCATCGTGTCATTCTCTATACTAAGACGGATAGGCTGGAGTTTACAGCGAGTCTAGAGGA
GGTTCTCAAGCAGGAACCCCGTCTCTTGCAGTGTCACCGCTCTTTTCTCATCAATCCTGCAAATGTGGTGCATTTAGATA
AGAAAGAAAAACTGCTTTTCTTTCCCAATGGGAGAAGCTGTCTAATCGCGCGTTACAAGGTCAGGGAAGTGTCTGAAGCT
ATCAATAACTTACACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

54.733

99.184

0.543
  comE/comE1 Streptococcus equinus JB1

43.46

96.735

0.42
  comE/comE2 Streptococcus equinus JB1

38.43

98.776

0.38
  comE Streptococcus infantis strain Atu-4

36.179

100

0.363

Multiple sequence alignment