Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   D7D50_RS09040 Genome accession   NZ_CP032620
Coordinates   1808055..1808729 (-) Length   224 a.a.
NCBI ID   WP_117744091.1    Uniprot ID   -
Organism   Streptococcus koreensis strain KCOM 2890 (=JS71)     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1803055..1813729
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7D50_RS09020 (D7D50_09020) - 1803104..1804192 (+) 1089 WP_120702075.1 DEAD/DEAH box helicase -
  D7D50_RS09025 (D7D50_09025) - 1804374..1805759 (-) 1386 WP_120702077.1 polysaccharide deacetylase family protein -
  D7D50_RS09030 (D7D50_09030) - 1805950..1806336 (-) 387 WP_023022851.1 VOC family protein -
  D7D50_RS09035 (D7D50_09035) ciaH 1806692..1808065 (-) 1374 WP_120702079.1 sensor histidine kinase Regulator
  D7D50_RS09040 (D7D50_09040) ciaR 1808055..1808729 (-) 675 WP_117744091.1 response regulator transcription factor Regulator
  D7D50_RS09045 (D7D50_09045) - 1808840..1809286 (-) 447 WP_120702081.1 hypothetical protein -
  D7D50_RS09050 (D7D50_09050) - 1809496..1810038 (+) 543 WP_120702082.1 biotin transporter BioY -
  D7D50_RS09055 (D7D50_09055) - 1810093..1812636 (-) 2544 WP_120702084.1 M1 family metallopeptidase -
  D7D50_RS09060 (D7D50_09060) phoU 1812767..1813420 (-) 654 WP_023022840.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25235.99 Da        Isoelectric Point: 4.3669

>NTDB_id=317153 D7D50_RS09040 WP_117744091.1 1808055..1808729(-) (ciaR) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGDEGLYEAESGIYDLILLDLMLPGKDGFQVLKELRDKGVSTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKVNENTLSYGNVTVNLSTNSTLVEGKEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTDFAKNLQTLRSVGYILKDAQ

Nucleotide


Download         Length: 675 bp        

>NTDB_id=317153 D7D50_RS09040 WP_117744091.1 1808055..1808729(-) (ciaR) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
ATGATTAAGATTTTATTAGTCGAAGATGACCTTGGTTTGTCTAATTCAGTATTTGATTTTTTAGATGATTTTGCAGATGT
CATGCAAGTCTTTGATGGGGATGAAGGTTTGTATGAGGCTGAAAGTGGGATCTATGACCTAATTTTACTGGACCTCATGC
TTCCTGGCAAAGATGGTTTCCAAGTTCTAAAAGAATTGAGAGATAAGGGGGTCTCCACTCCGGTATTGATTATGACAGCC
AAAGAGAGCTTGGACGATAAGGGCCATGGTTTTGAGTTGGGAGCAGATGACTATCTGACCAAGCCTTTCTACCTAGAAGA
GTTGAAAATGCGAATCCAAGCATTGTTGAAGCGCGCTGGTAAGGTCAATGAAAATACTCTTTCTTATGGGAATGTGACCG
TTAATCTCTCGACTAACTCTACGCTTGTTGAAGGGAAAGAAGTAGAACTATTAGGAAAAGAATTTGATCTTTTGGTCTAT
TTCCTTCAAAATCAAAATGTCATCCTGCCAAAAACACAAATCTTTGATCGACTTTGGGGATTTGATAGCGATACGACCAT
TTCGGTTGTCGAAGTGTATGTTTCTAAGATTCGGAAGAAATTAAAAGGTACAGACTTTGCAAAAAATCTCCAAACATTGC
GTAGCGTGGGGTATATTCTGAAAGATGCTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

89.732

100

0.897
  ciaR Streptococcus pneumoniae D39

89.732

100

0.897
  ciaR Streptococcus pneumoniae R6

89.732

100

0.897
  ciaR Streptococcus pneumoniae TIGR4

89.732

100

0.897
  ciaR Streptococcus mutans UA159

87.054

100

0.871
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.428

100

0.393
  vicR Streptococcus mutans UA159

34.764

100

0.362

Multiple sequence alignment