Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   D7D50_RS09035 Genome accession   NZ_CP032620
Coordinates   1806692..1808065 (-) Length   457 a.a.
NCBI ID   WP_120702079.1    Uniprot ID   -
Organism   Streptococcus koreensis strain KCOM 2890 (=JS71)     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1801692..1813065
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7D50_RS09015 (D7D50_09015) - 1802125..1803102 (+) 978 WP_120702073.1 Gfo/Idh/MocA family protein -
  D7D50_RS09020 (D7D50_09020) - 1803104..1804192 (+) 1089 WP_120702075.1 DEAD/DEAH box helicase -
  D7D50_RS09025 (D7D50_09025) - 1804374..1805759 (-) 1386 WP_120702077.1 polysaccharide deacetylase family protein -
  D7D50_RS09030 (D7D50_09030) - 1805950..1806336 (-) 387 WP_023022851.1 VOC family protein -
  D7D50_RS09035 (D7D50_09035) ciaH 1806692..1808065 (-) 1374 WP_120702079.1 sensor histidine kinase Regulator
  D7D50_RS09040 (D7D50_09040) ciaR 1808055..1808729 (-) 675 WP_117744091.1 response regulator transcription factor Regulator
  D7D50_RS09045 (D7D50_09045) - 1808840..1809286 (-) 447 WP_120702081.1 hypothetical protein -
  D7D50_RS09050 (D7D50_09050) - 1809496..1810038 (+) 543 WP_120702082.1 biotin transporter BioY -
  D7D50_RS09055 (D7D50_09055) - 1810093..1812636 (-) 2544 WP_120702084.1 M1 family metallopeptidase -

Sequence

Protein


Download         Length: 457 a.a.        Molecular weight: 52385.77 Da        Isoelectric Point: 6.7520

>NTDB_id=317152 D7D50_RS09035 WP_120702079.1 1806692..1808065(-) (ciaH) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
MLNKIKKTVNADDFSYFIRYFGLFTLIFSTMTLIIIQVMRSSLYTTVDENLKMLSKDRYSIISLANRTGNGMGRDETADD
GPEDDELGPEDGPRPSVTSNSTAILLNDKFENVTTDNGFLDLKTVTFSRSYLNKIKQIQITNHYKQKESYRAYLVDIDPD
DYIDGVKYAVIMTNISQLEQTSEKHESQIALVMICFWGISLFASIFLAKMSVKPLLESMNRQKAFVENASHELRTPLAVL
QNRLETLFRKPEATIMESSENIASSLDEVRNMRLLTTNLLNLARRDDGIKPEFCEITPSFFDQTFANYEIIAEENEKIFE
YENLVDRSLVTDKVLLKQLMTILYDNALKYTEEEGKIRFVAQFKDRYLYLRVEDNGPGIADEDKKRIFDRFYRVDKARTR
QKGGFGLGLSLAKQIVEAFNGTISVRDNKPKGSIFEVKLATKSESKKRSSSKSTKNK

Nucleotide


Download         Length: 1374 bp        

>NTDB_id=317152 D7D50_RS09035 WP_120702079.1 1806692..1808065(-) (ciaH) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
ATGCTCAATAAAATTAAAAAAACTGTCAATGCGGATGACTTTTCTTATTTCATCCGCTATTTCGGACTCTTTACCTTGAT
TTTCTCAACCATGACCTTGATTATTATTCAGGTGATGCGTTCCAGTCTTTATACAACGGTTGACGAAAATTTAAAAATGC
TCAGTAAAGATCGCTATTCGATTATCAGTTTGGCAAACCGTACAGGCAATGGGATGGGAAGAGACGAAACTGCTGATGAC
GGCCCAGAAGATGATGAACTTGGTCCCGAGGATGGCCCTAGACCATCGGTTACTTCCAATAGCACAGCTATCCTTTTGAA
TGATAAATTTGAAAATGTGACGACGGATAATGGTTTCCTAGATCTAAAAACAGTAACTTTTAGTCGCAGTTATTTAAACA
AAATCAAGCAGATTCAAATTACCAATCATTATAAGCAGAAGGAAAGTTACCGGGCTTATTTGGTAGATATTGATCCCGAT
GATTATATCGACGGGGTGAAATATGCCGTGATCATGACCAATATCAGTCAGTTGGAACAGACCAGTGAAAAACATGAGAG
TCAAATTGCCTTGGTCATGATTTGTTTCTGGGGCATTTCCCTCTTTGCAAGTATCTTCCTGGCTAAGATGAGTGTGAAAC
CTCTCTTAGAGAGCATGAACCGGCAGAAGGCCTTCGTCGAAAATGCCTCTCATGAATTGCGGACGCCTTTAGCGGTTTTG
CAAAATCGTTTGGAAACCTTATTCCGCAAACCAGAGGCAACGATTATGGAATCTAGTGAGAATATCGCCTCCTCTTTGGA
TGAAGTTCGCAATATGCGCTTATTGACGACCAATCTCTTAAACTTAGCCCGTCGAGATGATGGGATTAAACCGGAGTTTT
GCGAGATCACACCATCCTTTTTTGATCAAACTTTTGCCAATTATGAAATCATTGCGGAGGAAAACGAAAAAATCTTCGAA
TATGAGAATCTGGTGGATAGGAGTCTGGTGACTGATAAGGTCCTATTGAAACAACTGATGACCATTTTGTATGATAATGC
CCTCAAATATACGGAGGAAGAAGGGAAAATACGCTTTGTCGCCCAATTCAAGGATCGTTATCTCTATCTTCGAGTAGAGG
ACAATGGTCCAGGAATTGCTGATGAAGATAAAAAACGGATTTTTGATCGTTTCTATCGAGTGGATAAAGCGCGAACCCGT
CAAAAGGGTGGTTTTGGTTTAGGCTTATCCTTAGCCAAGCAAATCGTAGAAGCCTTCAATGGTACCATTAGTGTTCGAGA
TAACAAACCTAAAGGTTCTATTTTCGAGGTAAAACTAGCAACTAAGTCAGAAAGTAAAAAGAGATCCAGTTCTAAATCAA
CGAAGAACAAGTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(223-288)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(332-439)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

60.356

98.249

0.593
  ciaH Streptococcus pneumoniae D39

60.356

98.249

0.593
  ciaH Streptococcus pneumoniae R6

60.356

98.249

0.593
  ciaH Streptococcus pneumoniae TIGR4

60.356

98.249

0.593
  ciaH Streptococcus mutans UA159

51.025

96.061

0.49

Multiple sequence alignment