Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   D7D50_RS04610 Genome accession   NZ_CP032620
Coordinates   900176..900913 (-) Length   245 a.a.
NCBI ID   WP_120701613.1    Uniprot ID   -
Organism   Streptococcus koreensis strain KCOM 2890 (=JS71)     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 895176..905913
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7D50_RS04580 (D7D50_04580) - 895510..895734 (+) 225 WP_023024418.1 DUF4649 family protein -
  D7D50_RS04585 (D7D50_04585) trxA 895747..896061 (+) 315 WP_023024416.1 thioredoxin -
  D7D50_RS04590 (D7D50_04590) - 896189..896962 (-) 774 WP_120701609.1 hypothetical protein -
  D7D50_RS04595 (D7D50_04595) - 896964..897839 (-) 876 WP_120701610.1 ABC transporter ATP-binding protein -
  D7D50_RS04600 (D7D50_04600) - 897892..898641 (-) 750 WP_120701611.1 amino acid transporter -
  D7D50_RS04605 (D7D50_04605) - 898842..900179 (-) 1338 WP_120701612.1 sensor histidine kinase -
  D7D50_RS04610 (D7D50_04610) comE/blpR 900176..900913 (-) 738 WP_120701613.1 response regulator transcription factor Regulator
  D7D50_RS04615 (D7D50_04615) pepF 901387..903183 (-) 1797 WP_120701614.1 oligoendopeptidase F -
  D7D50_RS04620 (D7D50_04620) - 903360..904676 (+) 1317 WP_120701615.1 DUF6287 domain-containing protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28428.46 Da        Isoelectric Point: 6.8335

>NTDB_id=317139 D7D50_RS04610 WP_120701613.1 900176..900913(-) (comE/blpR) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
MLNIFVLEDDFLQQTRIETAIKKCMTDHHLKYKYLEVFGKPTQLLEAIKETGNHQFFFLDIEIKGEEKKGMEIAREIREK
DPSASIVFVTTHSEFMPVTYRYRVSALDFIDKGLNDQDYQEAISSVLIHAAENVNKTIGEDSFSFKSEHSQIQVPFSDIL
YFETSSTVHKVVLTTKKGHMEFYGKVSDIAKTDKRLYQSHRAYVVNPENVVRIDKANHIVYFENNESCFVSRLKLKGLVE
KVDKK

Nucleotide


Download         Length: 738 bp        

>NTDB_id=317139 D7D50_RS04610 WP_120701613.1 900176..900913(-) (comE/blpR) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
ATGCTAAATATCTTTGTATTAGAAGATGATTTTCTACAACAAACTCGTATTGAAACAGCAATCAAGAAATGTATGACAGA
TCATCATCTAAAGTATAAATACTTAGAGGTATTTGGGAAGCCAACACAATTGTTAGAGGCCATCAAAGAGACAGGAAATC
ACCAATTCTTTTTTTTAGATATTGAAATTAAAGGGGAAGAAAAAAAAGGAATGGAAATTGCGCGTGAGATTCGTGAAAAA
GATCCTAGCGCTTCAATCGTATTCGTAACGACTCACTCAGAATTCATGCCCGTTACCTATCGTTATCGTGTCTCCGCTTT
GGATTTTATTGATAAAGGATTAAATGATCAGGATTATCAGGAAGCGATCTCATCTGTTTTGATACATGCTGCTGAGAACG
TCAATAAGACAATAGGGGAGGATTCCTTCAGCTTTAAATCAGAGCATTCCCAGATTCAAGTCCCTTTCTCAGATATTCTA
TATTTTGAGACATCTTCGACCGTTCATAAGGTCGTTTTAACAACTAAAAAAGGACACATGGAATTTTATGGTAAAGTCTC
AGATATTGCTAAAACCGACAAGCGACTTTACCAAAGTCATCGAGCTTACGTTGTAAATCCAGAGAATGTCGTTCGTATTG
ATAAAGCAAATCATATTGTTTATTTTGAAAACAATGAATCATGCTTTGTATCACGTTTAAAACTGAAGGGGCTAGTTGAA
AAGGTAGATAAAAAATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(152-241)

Response regulator receiver domain (Response_reg)

(4-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

58.159

97.551

0.567
  comE/comE1 Streptococcus equinus JB1

49.174

98.776

0.486
  comE/comE2 Streptococcus equinus JB1

40.329

99.184

0.4
  comE/comE2 Streptococcus gordonii strain NCTC7865

36.626

99.184

0.363
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

36.626

99.184

0.363
  comE Streptococcus infantis strain Atu-4

35.743

100

0.363

Multiple sequence alignment