Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   D7D50_RS03305 Genome accession   NZ_CP032620
Coordinates   602535..604688 (+) Length   717 a.a.
NCBI ID   WP_023027411.1    Uniprot ID   -
Organism   Streptococcus koreensis strain KCOM 2890 (=JS71)     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 597535..609688
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7D50_RS03285 (D7D50_03285) rplI 598957..599409 (+) 453 WP_120701454.1 50S ribosomal protein L9 -
  D7D50_RS03290 (D7D50_03290) dnaB 599434..600789 (+) 1356 WP_120701455.1 replicative DNA helicase -
  D7D50_RS03295 (D7D50_03295) - 600793..601065 (+) 273 WP_006595358.1 Veg family protein -
  D7D50_RS03300 (D7D50_03300) rpsD 601639..602250 (+) 612 WP_003009175.1 30S ribosomal protein S4 -
  D7D50_RS03305 (D7D50_03305) comA 602535..604688 (+) 2154 WP_023027411.1 peptide cleavage/export ABC transporter ComA Regulator
  D7D50_RS03310 (D7D50_03310) comB 604715..606076 (+) 1362 WP_120701456.1 bacteriocin secretion accessory protein Regulator
  D7D50_RS03315 (D7D50_03315) - 606113..606649 (-) 537 WP_023027409.1 TetR/AcrR family transcriptional regulator -
  D7D50_RS03320 (D7D50_03320) - 606785..609580 (+) 2796 WP_120701457.1 YhgE/Pip domain-containing protein -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 81000.60 Da        Isoelectric Point: 8.4289

>NTDB_id=317133 D7D50_RS03305 WP_023027411.1 602535..604688(+) (comA) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
MGFKKKHYRQQVDMRDCGVAALAMVFGYYGSYYSLASLREKAKTTADGTTALGLVKVAEELGFETRAFRADRTLFDLEGV
TYPLIVHVIKDGRLPHYYVVYKKDKKHLYVADPDPKVKMTKLTIEEFEKEWTGIVIALAPTPAYQPSKEKKNGLLDFVPL
LFKQRQLVLHIVLATLLVTLINIVGSYYLQSIIDTYVPDQMKQTLTVISLGLIVVYILQQILTYAQDYLLLVLGQRLSID
VILSYIKHVFQLPMSFFATRRTGEVVSRFTDANRIIDALASTLLSIFLDLSIVLILSVVLFSQNAHLFFLTILLLPIYAV
IIFAFMKPFERLNNETMEANSVLSSSIIEDINGIETIKSLTSERSRYQKIDSEFVDYLKKSFAMSKAESLQKGLKHLAQL
ILNVLVLWMGAHLVMKQELSLGQLITYNTLLVYFTGPLENLINLQTKLQAARVANTRLNEVYLIDSEFAEKKPLQEREAL
DGDLVFEGVDYKYGFGANVLTDINLRIKRGSKVSFVGISGSGKTTLAKMMVNFYQPTKGTIRLGGRDIQQVDKTLLRQQI
NYLPQQPYVFNGTILENLLLGAREGTSQEDILRAVEIAGIREDIERMPLNYQTELTTDGMGISGGQRQRIALARALLTDA
PILILDEATSSLDILTEKKIVDRLMALDKTIIFIAHRLTIAERSEKVFLMDQGCLKEEGSHEELLKKNGYYSHLVTC

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=317133 D7D50_RS03305 WP_023027411.1 602535..604688(+) (comA) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
ATGGGATTTAAGAAAAAACATTATCGCCAACAAGTTGACATGAGAGACTGTGGTGTTGCAGCTTTAGCCATGGTCTTTGG
CTACTATGGATCATACTATTCTTTAGCTAGTCTGCGGGAGAAGGCAAAAACGACTGCAGATGGAACGACTGCCTTAGGTT
TGGTCAAGGTAGCTGAAGAGTTGGGCTTTGAGACACGCGCCTTTCGAGCAGACCGCACTCTTTTTGACTTAGAAGGAGTG
ACCTATCCATTGATTGTCCACGTGATCAAGGATGGGCGTCTCCCTCATTATTACGTAGTGTATAAGAAAGATAAAAAACA
TCTTTACGTAGCAGATCCAGATCCAAAAGTAAAGATGACCAAATTGACGATCGAAGAGTTTGAAAAGGAATGGACAGGGA
TTGTCATTGCCTTGGCCCCGACTCCGGCCTATCAACCTAGTAAGGAAAAGAAAAATGGGCTCCTAGACTTTGTCCCTCTT
TTGTTTAAACAGCGACAATTGGTCCTTCATATTGTTCTTGCAACTTTATTGGTAACCCTTATCAATATTGTTGGTTCTTA
CTACCTACAATCAATTATTGATACCTATGTGCCTGATCAGATGAAGCAGACCTTGACTGTGATTTCACTAGGTTTGATTG
TGGTTTACATCTTACAGCAAATCCTCACCTACGCTCAGGATTATTTGCTCTTGGTATTAGGTCAACGCTTGTCTATTGAT
GTCATTCTGTCCTATATTAAGCATGTTTTTCAGTTGCCCATGAGTTTCTTTGCAACTCGACGGACAGGGGAAGTGGTGTC
GCGGTTTACAGATGCCAACCGCATTATCGATGCTCTGGCTAGTACGCTGCTTTCAATCTTTTTGGATCTGTCCATTGTTT
TGATTTTATCCGTAGTCCTGTTTAGCCAAAACGCTCACCTCTTTTTCTTGACCATTCTCTTGCTGCCGATTTATGCAGTC
ATTATTTTTGCCTTTATGAAGCCTTTTGAGCGCTTAAATAATGAAACTATGGAAGCCAATAGTGTCTTGTCTTCTTCTAT
TATCGAAGATATCAATGGGATTGAAACCATCAAGTCTCTTACCAGTGAGCGTAGTCGTTATCAAAAGATTGACTCAGAAT
TTGTGGATTATCTGAAGAAGTCCTTTGCCATGAGCAAGGCGGAAAGTCTTCAAAAGGGGCTCAAGCACTTGGCTCAGTTG
ATTTTGAATGTTTTGGTCTTGTGGATGGGAGCTCATTTGGTCATGAAGCAAGAATTGAGTTTGGGTCAGCTGATTACTTA
CAATACTCTCCTTGTTTATTTCACAGGGCCTCTAGAGAATTTGATCAACCTCCAAACCAAACTTCAAGCCGCCCGAGTAG
CTAATACCCGTCTGAATGAAGTCTATCTGATAGACTCTGAGTTCGCAGAGAAGAAGCCCCTTCAAGAGCGTGAGGCTCTC
GATGGTGATCTAGTATTTGAGGGAGTAGATTACAAGTACGGTTTCGGGGCCAATGTTCTAACAGATATTAACTTAAGAAT
CAAAAGAGGGAGCAAGGTCAGTTTTGTCGGTATTTCAGGTTCTGGAAAAACAACGCTAGCTAAAATGATGGTGAATTTCT
ACCAACCCACTAAAGGAACGATTCGTCTGGGAGGAAGGGATATCCAGCAAGTGGATAAAACCTTGCTCCGCCAGCAAATC
AATTATTTACCCCAGCAGCCCTATGTCTTTAATGGCACAATCTTAGAGAACTTGCTACTAGGAGCACGGGAAGGAACGAG
TCAGGAAGATATCTTGCGCGCTGTTGAAATCGCAGGAATTCGAGAAGATATTGAGCGCATGCCCCTCAATTACCAAACGG
AATTAACAACGGATGGTATGGGAATTTCTGGTGGACAACGGCAGCGGATTGCTTTGGCGCGTGCTTTGTTAACGGACGCT
CCTATTCTGATTCTGGATGAAGCGACCAGCAGCCTAGATATCTTGACGGAGAAGAAAATTGTGGACCGCTTGATGGCCTT
AGATAAGACCATTATCTTTATCGCCCATCGGTTAACGATTGCAGAACGGTCTGAAAAAGTCTTCCTCATGGACCAAGGTT
GTCTTAAGGAAGAAGGAAGCCATGAAGAATTACTGAAAAAGAATGGCTATTACAGCCATTTGGTTACTTGTTAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(171-438)

Peptidase C39 family (Peptidase_C39)

(6-142)

ABC transporter (ABC_tran)

(500-650)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

76.709

100

0.767
  comA Streptococcus mitis NCTC 12261

75.174

100

0.752
  comA Streptococcus pneumoniae Rx1

75.035

100

0.75
  comA Streptococcus pneumoniae D39

75.035

100

0.75
  comA Streptococcus pneumoniae R6

75.035

100

0.75
  comA Streptococcus mitis SK321

75.035

100

0.75
  comA Streptococcus pneumoniae TIGR4

74.616

100

0.746
  comA/nlmT Streptococcus mutans UA159

63.217

99.721

0.63

Multiple sequence alignment