Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilE   Type   Machinery gene
Locus tag   TFGA2_RS12390 Genome accession   NZ_CP032398
Coordinates   2110700..2111200 (-) Length   166 a.a.
NCBI ID   WP_134797874.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain TFG-A2     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2105700..2116200
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TFGA2_RS12370 (TFGA2_02175) msrAB 2106100..2107668 (-) 1569 WP_003687002.1 bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB -
  TFGA2_RS12375 (TFGA2_02176) pilA 2107814..2109067 (+) 1254 WP_003696286.1 signal recognition particle-docking protein FtsY Machinery gene
  TFGA2_RS12380 (TFGA2_02177) - 2109331..2110143 (-) 813 WP_134797873.1 opacity family porin -
  TFGA2_RS12390 (TFGA2_02178) pilE 2110700..2111200 (-) 501 WP_134797874.1 pilin Machinery gene
  TFGA2_RS12395 - 2111569..2111712 (-) 144 WP_003691943.1 hypothetical protein -
  TFGA2_RS14130 - 2112015..2112118 (-) 104 Protein_2137 pilin -
  TFGA2_RS12410 (TFGA2_02179) pilE 2112256..2112687 (-) 432 WP_050170900.1 pilin Machinery gene
  TFGA2_RS12415 (TFGA2_02180) lpxC 2112794..2113717 (-) 924 WP_003687007.1 UDP-3-O-acyl-N-acetylglucosamine deacetylase -
  TFGA2_RS12420 (TFGA2_02181) - 2114078..2114308 (-) 231 Protein_2140 hypothetical protein -
  TFGA2_RS12425 (TFGA2_02182) - 2114305..2115048 (-) 744 WP_003687014.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  TFGA2_RS12430 (TFGA2_02183) gmhB 2115078..2115641 (-) 564 WP_003687015.1 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase -

Sequence

Protein


Download         Length: 166 a.a.        Molecular weight: 17994.35 Da        Isoelectric Point: 5.2797

>NTDB_id=315413 TFGA2_RS12390 WP_134797874.1 2110700..2111200(-) (pilE) [Neisseria gonorrhoeae strain TFG-A2]
MNTLQKGFTLIELMIVIAIVGILAAVALPAYQDYTARAQVSEAILLAEGQKSAVTEYYLNHGEWPENNTSAGVASSPTDI
KGKYVEKVEVAKGVVTATMKSDGVNKEIQGKRLSLWAKREDGSVKWFCGQPVQRDDGKADNDAVADDKNNNGIDTKHLPS
TCRDLP

Nucleotide


Download         Length: 501 bp        

>NTDB_id=315413 TFGA2_RS12390 WP_134797874.1 2110700..2111200(-) (pilE) [Neisseria gonorrhoeae strain TFG-A2]
ATGAATACCCTTCAAAAAGGCTTTACCCTTATCGAGCTGATGATTGTGATCGCCATCGTCGGCATTTTGGCGGCAGTCGC
CCTTCCCGCCTACCAAGACTACACCGCCCGCGCGCAAGTTTCCGAAGCCATCCTTTTGGCCGAAGGTCAAAAATCAGCCG
TTACCGAGTATTACCTGAATCACGGCGAATGGCCGGAAAACAACACTTCTGCCGGCGTGGCATCCTCCCCCACCGACATC
AAAGGCAAATATGTTGAGAAAGTTGAAGTCGCAAAAGGCGTCGTTACCGCCACAATGAAATCAGACGGCGTAAACAAAGA
AATCCAAGGCAAAAGACTCTCCCTGTGGGCCAAGCGTGAAGACGGTTCGGTAAAATGGTTCTGCGGACAGCCGGTTCAGC
GCGACGACGGCAAAGCCGACAACGACGCCGTTGCCGACGACAAAAACAACAACGGCATCGACACCAAGCACCTGCCGTCA
ACCTGCCGTGACCTGCCGTGA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(5-28)

Pilin (bacterial filament) (Pilin)

(36-163)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilE Neisseria gonorrhoeae MS11

84.146

98.795

0.831
  pilE Neisseria gonorrhoeae strain FA1090

84.146

98.795

0.831
  pilA/pilA1 Eikenella corrodens VA1

36.932

100

0.392
  pilE Neisseria elongata subsp. glycolytica ATCC 29315

32.663

100

0.392
  comP Acinetobacter baylyi ADP1

36.628

100

0.38
  pilA Ralstonia pseudosolanacearum GMI1000

34.682

100

0.361

Multiple sequence alignment