Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   D2E16_RS08455 Genome accession   NZ_CP032064
Coordinates   1762227..1762931 (-) Length   234 a.a.
NCBI ID   WP_024376690.1    Uniprot ID   -
Organism   Streptococcus suis strain YSJ17     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1757227..1767931
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D2E16_RS08440 (D2E16_08700) vga(F) 1758158..1759543 (-) 1386 WP_225620735.1 ABC-F type ribosomal protection protein Vga(F) -
  D2E16_RS08445 (D2E16_08710) vicX 1760075..1760878 (-) 804 WP_004298858.1 MBL fold metallo-hydrolase Regulator
  D2E16_RS08450 (D2E16_08715) micB 1760885..1762234 (-) 1350 WP_002935841.1 cell wall metabolism sensor histidine kinase VicK Regulator
  D2E16_RS08455 (D2E16_08720) micA 1762227..1762931 (-) 705 WP_024376690.1 response regulator YycF Regulator
  D2E16_RS08460 (D2E16_08725) - 1763125..1763886 (+) 762 WP_172014668.1 amino acid ABC transporter ATP-binding protein -
  D2E16_RS08465 (D2E16_08730) - 1763897..1764736 (+) 840 WP_192368965.1 transporter substrate-binding domain-containing protein -
  D2E16_RS08470 (D2E16_08735) - 1764751..1765449 (+) 699 WP_024401921.1 amino acid ABC transporter permease -
  D2E16_RS08475 (D2E16_08740) - 1765464..1766123 (+) 660 WP_014637676.1 amino acid ABC transporter permease -
  D2E16_RS08480 (D2E16_08745) - 1766246..1767283 (+) 1038 WP_192368964.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26793.83 Da        Isoelectric Point: 4.8957

>NTDB_id=313539 D2E16_RS08455 WP_024376690.1 1762227..1762931(-) (micA) [Streptococcus suis strain YSJ17]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESIGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=313539 D2E16_RS08455 WP_024376690.1 1762227..1762931(-) (micA) [Streptococcus suis strain YSJ17]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACGCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTATTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGTTGCCAGAATTGGACGGACTAGAGGTTGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAACCCTTCTCTAATCGCGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAATAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTCGCTAAGAAGCATGGCAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAGATTGAAGATACAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.479

100

0.825
  vicR Streptococcus mutans UA159

80.426

100

0.808
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.348

98.291

0.436
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

37.975

100

0.385

Multiple sequence alignment