Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   D2E16_RS00350 Genome accession   NZ_CP032064
Coordinates   67537..68436 (+) Length   299 a.a.
NCBI ID   WP_024377696.1    Uniprot ID   A0A426GBG3
Organism   Streptococcus suis strain YSJ17     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 66833..67222 67537..68436 flank 315


Gene organization within MGE regions


Location: 66833..68436
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D2E16_RS00345 (D2E16_00360) tnpA 66833..67327 (+) 495 Protein_49 IS200/IS605 family transposase -
  D2E16_RS00350 (D2E16_00365) comR 67537..68436 (+) 900 WP_024377696.1 helix-turn-helix domain-containing protein Regulator

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35386.27 Da        Isoelectric Point: 4.3157

>NTDB_id=313501 D2E16_RS00350 WP_024377696.1 67537..68436(+) (comR) [Streptococcus suis strain YSJ17]
MNDKEFGQRVRQLRETASLTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYENEELMEKRADMMTEIYDDYYDDLPEEEKIAIDAIQSIIDVFETKTAEFGQDILEDYFEQIQRKPQFSAND
LLIIRLYLINLRMEIKQSSDFQHFLELVEKLPSQVELIESGELFILRDVMLTSIGILGEHEEYGKIPPLFDALDRIMVST
QDFQKKPILNLLKWKYELYVNNDSEEARRFYEEAVMFAKLIGDSHLVEKLESSWREEEK

Nucleotide


Download         Length: 900 bp        

>NTDB_id=313501 D2E16_RS00350 WP_024377696.1 67537..68436(+) (comR) [Streptococcus suis strain YSJ17]
ATGAACGATAAGGAATTTGGACAACGTGTACGTCAACTTCGAGAAACCGCTAGTCTGACACGTGAACAGTTTTGCGATGA
CGAACTTGAGCTCTCCGTCCGCCAATTAACCCGTATCGAAGCAGGCACTTCCAAGCCGACTTTTTCAAAAATCCAATATA
TCGCAACCCGCTTAGGCATGGGGCTCTACGAGCTTATGCCAGATTACGTGTCGCTACCTGAACGATATTCCAAACTGAAG
TTTGATGTACTTCGTACACCGACTTATGAAAATGAGGAATTGATGGAAAAACGGGCAGATATGATGACAGAAATCTATGA
TGACTATTATGATGACTTGCCTGAAGAAGAGAAAATAGCGATTGATGCCATTCAATCTATTATTGATGTATTTGAAACGA
AGACAGCAGAATTTGGTCAAGATATTCTAGAAGATTATTTTGAACAAATCCAAAGAAAACCCCAATTTTCAGCCAACGAT
TTGTTGATAATTCGACTCTATTTAATCAATTTGAGAATGGAAATTAAACAGAGCAGTGATTTTCAGCACTTTTTAGAGTT
GGTGGAAAAGTTACCAAGCCAAGTAGAATTGATTGAATCTGGAGAATTATTTATTTTAAGAGATGTGATGCTGACGTCGA
TAGGGATTCTTGGCGAACATGAAGAATATGGCAAGATACCTCCACTTTTTGATGCTCTAGATAGAATCATGGTTTCAACT
CAAGATTTTCAAAAGAAACCCATTCTCAATCTGCTTAAGTGGAAATATGAGTTATATGTGAACAATGATAGCGAGGAGGC
TAGACGGTTTTATGAAGAAGCAGTTATGTTCGCAAAATTAATTGGAGACTCCCATTTAGTAGAAAAATTAGAATCATCAT
GGAGAGAAGAGGAAAAGTGA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-294)

Helix-turn-helix domain (HTH_31)

(5-60)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A426GBG3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

68.475

98.662

0.676
  comR Streptococcus suis 05ZYH33

68.475

98.662

0.676
  comR Streptococcus suis D9

61.873

100

0.619
  comR Streptococcus mutans UA159

42.14

100

0.421
  comR Streptococcus pyogenes MGAS8232

37.71

99.331

0.375
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

38.542

96.321

0.371
  comR Streptococcus pyogenes MGAS315

36.486

98.997

0.361

Multiple sequence alignment