Detailed information NTG0312361

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: D1O36_RS10025
• Genome accession: NZ_CP031881
• Coordinates: 1853777..1855012 (+)
• Length: 411 a.a.
• NCBI ID: WP_134973549.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain ST106
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1848777..1860012

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1O36_RS09995 (D1O36_10030)	-	1849245..1851851 (+)	2607	WP_134973548.1	YfhO family protein	-
D1O36_RS10015 (D1O36_10050)	-	1852395..1853078 (-)	684	WP_011226711.1	YoaK family protein	-
D1O36_RS10020 (D1O36_10055)	rlmH	1853094..1853572 (-)	479	Protein_1881	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
D1O36_RS10025 (D1O36_10060)	htrA	1853777..1855012 (+)	1236	WP_134973549.1	trypsin-like peptidase domain-containing protein	Regulator
D1O36_RS10030 (D1O36_10065)	spo0J	1855078..1855845 (+)	768	WP_002952299.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42972.30 Da
• Isoelectric Point: 4.7740

>NTDB_id=312361 D1O36_RS10025 WP_134973549.1 1853777..1855012(+) (htrA) [Streptococcus thermophilus strain ST106]
MKKFNWKKIVAPIAMLIIGLLGGLLGAFILLTAAGVSFTNTTDTRVKTAKTVYTNITDTTKAVKKVQNAVVSVINYQEGS
SSDSLNDLYGRIFGGGDSSDSSQENSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKITTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTITMQNDNGETVSTNAIQT
DAAINPGNSGAALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISIADLNSLS
SSATSKLDLPDEVKSGVVVGSVQKGMPADGKLQEYDVITEIDGKKISSKTDIQTNLYSHSIGDTIKVTFYRGKDKKTVDL
KLTKSTEDISD

Nucleotide

• Length: 1236 bp

>NTDB_id=312361 D1O36_RS10025 WP_134973549.1 1853777..1855012(+) (htrA) [Streptococcus thermophilus strain ST106]
ATGAAAAAATTTAACTGGAAGAAAATAGTCGCGCCAATTGCAATGCTAATTATTGGCTTACTAGGTGGTTTACTTGGTGC
CTTTATCCTACTAACAGCAGCCGGGGTATCTTTTACCAATACAACAGATACTCGAGTAAAAACGGCTAAGACCGTCTACA
CCAATATAACAGATACAACTAAGGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTATCAAGAAGGTTCA
TCTTCAGATTCTCTAAATGACCTTTATGGCCGTATCTTTGGCGGAGGGGACAGTTCTGATTCTAGCCAAGAAAATTCAAA
AGATTCAGATGGCCTGCAGGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGTAAAGAAGCCTACATCGTAA
CCAATAACCACGTTGTCGATGGGGCTAAAAAACTTGAAATCATGCTTTCGGATGGTTCGAAAATTACTGGTGAACTTGTT
GGTAAAGACACTTACTCTGACCTAGCAGTTGTCAAAGTATCTTCAGATAAAATAACAACTGTTGCAGAATTTGCAGACTC
AAACTCCCTTACTGTTGGTGAAAAAGCAATTGCTATTGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAAG
GAATCGTTTCTAGCCTTAGCCGTACTATAACGATGCAAAACGATAATGGTGAAACTGTATCAACAAACGCTATCCAAACA
GATGCAGCCATTAACCCTGGTAACTCTGGTGCTGCCCTAGTCAATATTGAAGGACAAGTTATCGGTATTAACTCAAGTAA
AATTTCATCAACGTCTGCAGTCGCTGGTAGTGCTGTTGAAGGTATGGGGTTTGCCATTCCATCAAACGATGTTGTTGAAA
TCATCAATCAATTAGAAAAAGATGGTAAAGTTACACGACCAGCACTAGGGATCTCAATAGCAGATCTTAATAGCCTTTCT
AGCAGCGCAACTTCTAAATTAGATTTACCAGATGAGGTCAAATCCGGTGTTGTTGTCGGTAGTGTTCAGAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAATATGATGTTATCACTGAGATTGATGGTAAGAAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATCGGAGATACTATCAAGGTAACCTTCTATCGTGGTAAAGATAAGAAAACTGTAGATCTT
AAATTAACAAAATCTACAGAAGACATATCTGATTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

• Peptidase family M50 (Peptidase_M50) (4-406)

• PDZ domain (PDZ_2) (307-402)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.538	98.054	0.603
htrA	Streptococcus gordonii str. Challis substr. CH1	57.039	100	0.572
htrA	Streptococcus mitis NCTC 12261	53.545	99.513	0.533
htrA	Streptococcus pneumoniae TIGR4	53.301	99.513	0.53
htrA	Streptococcus pneumoniae D39	53.301	99.513	0.53
htrA	Streptococcus pneumoniae Rx1	53.301	99.513	0.53
htrA	Streptococcus pneumoniae R6	53.301	99.513	0.53