Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE1   Type   Regulator
Locus tag   DDV21_RS08640 Genome accession   NZ_CP031733
Coordinates   1806862..1807593 (+) Length   243 a.a.
NCBI ID   WP_116877995.1    Uniprot ID   A0A372KM50
Organism   Streptococcus chenjunshii strain Z15     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1801862..1812593
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DDV21_RS08595 (DDV21_008595) - 1802093..1802284 (+) 192 WP_116877988.1 bacteriocin -
  DDV21_RS08605 (DDV21_008605) - 1802543..1802851 (+) 309 WP_116877989.1 bacteriocin immunity protein -
  DDV21_RS11950 - 1803374..1803442 (+) 69 WP_241964717.1 hypothetical protein -
  DDV21_RS08615 (DDV21_008615) - 1803814..1804071 (+) 258 WP_116877990.1 garvicin Q family class II bacteriocin -
  DDV21_RS08620 (DDV21_008620) - 1804071..1804379 (+) 309 WP_116877991.1 bacteriocin immunity protein -
  DDV21_RS08630 (DDV21_008630) - 1805127..1805411 (+) 285 WP_116877993.1 hypothetical protein -
  DDV21_RS08635 (DDV21_008635) - 1805512..1806483 (+) 972 WP_116877994.1 thioredoxin family protein -
  DDV21_RS08640 (DDV21_008640) comE/comE1 1806862..1807593 (+) 732 WP_116877995.1 response regulator transcription factor Regulator
  DDV21_RS08645 (DDV21_008645) - 1807601..1808908 (+) 1308 WP_116877996.1 GHKL domain-containing protein -
  DDV21_RS08650 (DDV21_008650) comC/comC1 1808927..1809067 (-) 141 WP_116877997.1 lactococcin family bacteriocin Regulator
  DDV21_RS08655 (DDV21_008655) - 1809327..1811687 (-) 2361 WP_116877998.1 DNA translocase FtsK -

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 28501.54 Da        Isoelectric Point: 6.6113

>NTDB_id=310849 DDV21_RS08640 WP_116877995.1 1806862..1807593(+) (comE/comE1) [Streptococcus chenjunshii strain Z15]
MLDIYILEDDIIQQFRMEREIEKIMSKNHWDYQRLEVFDSSKDIIAKASEKGEHQIFFLDLEIKEDEKQGIDVAKAIREK
DATAIIVFVTSHSEFMPITYQSLVGAIDFIDKNVSDQTFRARVELCLKEAIKHQTGNFGENSYLFETSKARVRVPYSDIL
YFETSPAVHRVILHTKTDRIEFYATIAEVAKSDKRLFKCHRSFVINADNVTRFDKRTRTAYFETGNYCLVSREKVKTLLN
EMR

Nucleotide


Download         Length: 732 bp        

>NTDB_id=310849 DDV21_RS08640 WP_116877995.1 1806862..1807593(+) (comE/comE1) [Streptococcus chenjunshii strain Z15]
ATGTTAGATATTTATATACTGGAAGATGATATCATTCAGCAGTTCCGTATGGAGCGCGAAATTGAAAAGATCATGTCCAA
AAATCACTGGGATTACCAAAGATTAGAGGTTTTCGATTCTTCAAAAGATATTATTGCTAAAGCATCTGAAAAGGGCGAAC
ACCAAATTTTCTTTCTGGACTTGGAAATTAAAGAGGATGAAAAACAAGGCATAGATGTTGCCAAGGCTATTCGCGAAAAA
GATGCAACAGCGATTATTGTTTTTGTCACAAGTCATTCAGAATTTATGCCTATAACCTATCAGTCTTTGGTGGGCGCCAT
TGATTTTATTGATAAAAATGTGAGTGATCAAACGTTCAGAGCGCGGGTAGAGCTGTGTTTAAAGGAAGCCATAAAACATC
AGACTGGCAATTTTGGCGAAAATTCTTATTTATTTGAAACGTCAAAAGCGCGGGTACGCGTCCCTTATAGCGATATCCTA
TATTTTGAGACATCTCCTGCTGTACATCGCGTCATCTTGCATACAAAAACTGACAGGATTGAGTTTTATGCTACTATAGC
TGAGGTTGCTAAATCGGATAAACGTCTCTTCAAATGCCACCGCTCTTTTGTTATCAATGCAGATAATGTCACAAGATTTG
ACAAAAGAACACGGACTGCCTACTTTGAAACAGGGAATTACTGCCTAGTTTCCAGAGAAAAAGTAAAAACTCTCTTAAAC
GAGATGAGGTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-123)

LytTr DNA-binding domain (LytTR)

(152-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A372KM50

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE1 Streptococcus equinus JB1

76.543

100

0.765
  comE/blpR Streptococcus mutans UA159

46.444

98.354

0.457
  comE/comE2 Streptococcus equinus JB1

43.802

99.588

0.436
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.317

100

0.366
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.317

100

0.366

Multiple sequence alignment