Detailed information NTG0310834

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DDV21_RS06155
• Genome accession: NZ_CP031733
• Coordinates: 1252945..1253787 (+)
• Length: 280 a.a.
• NCBI ID: WP_116877135.1
• Uniprot ID: A0A372KP54
• Organism: Streptococcus chenjunshii strain Z15
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1247945..1258787

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DDV21_RS06135 (DDV21_006135)	-	1248512..1249486 (+)	975	WP_116877397.1	iron chelate uptake ABC transporter family permease subunit	-
DDV21_RS06140 (DDV21_006140)	-	1249483..1250454 (+)	972	WP_116877138.1	iron chelate uptake ABC transporter family permease subunit	-
DDV21_RS06145 (DDV21_006145)	-	1250451..1251218 (+)	768	WP_116877137.1	ATP-binding cassette domain-containing protein	-
DDV21_RS06150 (DDV21_006150)	-	1251472..1252551 (+)	1080	WP_116877136.1	siderophore ABC transporter substrate-binding protein	-
DDV21_RS06155 (DDV21_006155)	dprA	1252945..1253787 (+)	843	WP_116877135.1	DNA-processing protein DprA	Machinery gene
DDV21_RS06160 (DDV21_006160)	topA	1253880..1256003 (+)	2124	WP_116877134.1	type I DNA topoisomerase	-
DDV21_RS06165 (DDV21_006165)	trmFO	1256276..1257610 (+)	1335	WP_116877133.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
DDV21_RS06170 (DDV21_006170)	-	1257696..1258220 (-)	525	WP_116877132.1	PASTA domain-containing protein	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 30878.72 Da
• Isoelectric Point: 9.4049

>NTDB_id=310834 DDV21_RS06155 WP_116877135.1 1252945..1253787(+) (dprA) [Streptococcus chenjunshii strain Z15]
MNNFELFKLKKAGLSNLNILNILSYQEQVKKSLSVRDMAVVSQCKNPVLFIEAYKNLNSKKLRQDFNRFSSISILDKIYP
PALKTIYNPPVLLYYSGNLDLLAKPKLAAVGGRLASETGTRAIQKIIKELSNHFVIVSGLARGIDTSAHLASLRNGGTTI
AVIGTGLDISYPEENHQLQTYISRHHLVLTEYEPGSPPLKFHFPERNRIIAGLVQGVIVAEAKKRSGSLITCERALEEGR
DVFAVPGNILDGKSDGCLHLIQEGAKCITSGFDIISEYQL

Nucleotide

• Length: 843 bp

>NTDB_id=310834 DDV21_RS06155 WP_116877135.1 1252945..1253787(+) (dprA) [Streptococcus chenjunshii strain Z15]
ATGAACAATTTTGAATTATTTAAACTTAAAAAAGCGGGACTCAGCAATCTTAATATCCTCAATATCCTGTCTTATCAAGA
ACAGGTGAAAAAGTCTTTATCCGTACGTGATATGGCTGTAGTGTCACAATGCAAAAATCCTGTTTTGTTTATTGAAGCTT
ACAAAAATTTAAACAGCAAAAAACTGCGCCAGGATTTTAATCGCTTTTCATCCATTTCAATACTGGATAAAATCTATCCT
CCAGCCTTAAAAACGATCTATAATCCTCCAGTCTTGCTCTATTATTCCGGAAATCTGGATTTACTGGCCAAGCCTAAATT
AGCAGCAGTGGGAGGACGTTTGGCATCTGAAACAGGAACAAGAGCGATTCAAAAAATTATTAAAGAACTCAGCAACCATT
TTGTCATTGTCAGCGGTTTAGCTCGCGGTATTGATACAAGCGCTCATTTGGCCAGTTTAAGGAACGGCGGGACAACAATC
GCGGTAATCGGAACCGGTTTGGATATCTCCTATCCTGAAGAAAATCATCAGCTGCAAACCTATATCAGCAGGCACCATCT
GGTTTTGACAGAATACGAACCCGGTTCTCCGCCTCTGAAATTTCATTTTCCTGAACGGAACCGCATTATTGCCGGACTGG
TGCAGGGAGTAATTGTGGCTGAAGCTAAAAAAAGGTCAGGCAGTTTAATTACCTGCGAAAGAGCTCTGGAAGAAGGCCGG
GATGTTTTTGCTGTTCCAGGAAACATTTTAGATGGAAAATCAGATGGCTGTCTCCATTTGATTCAAGAGGGGGCAAAGTG
TATTACAAGTGGGTTTGACATCATTTCTGAATATCAGCTGTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

3D structure

• AlphaFold DB: A0A372KP54

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	72.5	100	0.725
dprA/cilB/dalA	Streptococcus mitis SK321	60.714	100	0.607
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.357	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.357	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.357	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.357	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60	100	0.6
dprA	Lactococcus lactis subsp. cremoris KW2	58.633	99.286	0.582
dprA	Legionella pneumophila strain ERS1305867	45.228	86.071	0.389