Detailed information NTG0310807

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: DDV21_RS00415
• Genome accession: NZ_CP031733
• Coordinates: 71297..72211 (+)
• Length: 304 a.a.
• NCBI ID: WP_116878509.1
• Uniprot ID: -
• Organism: Streptococcus chenjunshii strain Z15
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 66297..77211

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DDV21_RS00395 (DDV21_000395)	-	66450..67409 (+)	960	WP_116878541.1	2-dehydropantoate 2-reductase N-terminal domain-containing protein	-
DDV21_RS00400 (DDV21_000400)	-	67420..67644 (+)	225	WP_116878506.1	phosphoribosylaminoimidazole carboxylase	-
DDV21_RS00405 (DDV21_000405)	purB	67946..69238 (+)	1293	WP_116878507.1	adenylosuccinate lyase	-
DDV21_RS00410 (DDV21_000410)	-	69428..70936 (+)	1509	WP_116878508.1	FAD-dependent oxidoreductase	-
DDV21_RS00415 (DDV21_000415)	comR	71297..72211 (+)	915	WP_116878509.1	helix-turn-helix domain-containing protein	Regulator
DDV21_RS00420 (DDV21_000420)	ruvB	72502..73503 (+)	1002	WP_116878542.1	Holliday junction branch migration DNA helicase RuvB	-
DDV21_RS00425 (DDV21_000425)	-	73626..74162 (+)	537	WP_116878510.1	hypothetical protein	-
DDV21_RS00430 (DDV21_000430)	-	74362..74802 (+)	441	WP_116878511.1	low molecular weight protein-tyrosine-phosphatase	-
DDV21_RS00435 (DDV21_000435)	-	74825..75205 (+)	381	WP_116878512.1	hypothetical protein	-
DDV21_RS00440 (DDV21_000440)	-	75202..76992 (+)	1791	WP_116878513.1	acyltransferase family protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35394.47 Da
• Isoelectric Point: 4.5836

>NTDB_id=310807 DDV21_RS00415 WP_116878509.1 71297..72211(+) (comR) [Streptococcus chenjunshii strain Z15]
MKKFGGKIKRLRLANKLTREELCGDETELSVRQLARIESGQSAPTLNKIRYIAKCLGVTVGELTDGESFALPARYEELKY
LIMRTPIYDDSSRVELVETYFDEIYEYYYNSLPEEEQLSIDVLQSSLDAHMTDNIEFGSGLLQDYFEQVKAKKVYGINDL
LLIGLYFYQSSSDHIYLDDTSLETLDMLAGRLVLQTRYIVPSHLFLLRDVLLQCSGLLLLTKSYQHLLTIVQELNTIISK
TQDYQKKPLVDMIEWKYYLYVDQDFSAAQLKYQQAVQFSVMIDDEILKENLEKEWRNDSLQLRT

Nucleotide

• Length: 915 bp

>NTDB_id=310807 DDV21_RS00415 WP_116878509.1 71297..72211(+) (comR) [Streptococcus chenjunshii strain Z15]
GTGAAAAAGTTTGGTGGGAAAATTAAACGTTTAAGGCTTGCAAATAAGCTGACACGGGAAGAACTTTGCGGAGATGAGAC
GGAGCTGTCTGTCAGGCAGCTGGCGCGGATTGAATCAGGGCAGTCAGCCCCTACGCTTAATAAAATAAGGTATATTGCTA
AATGTTTGGGAGTAACTGTTGGTGAGCTGACAGACGGTGAAAGTTTTGCCCTGCCTGCCCGTTATGAGGAACTGAAATAC
CTCATTATGAGGACACCGATATATGATGACAGCAGCCGGGTTGAATTGGTTGAGACTTACTTTGATGAGATATATGAATA
TTATTACAATAGCCTGCCCGAAGAAGAACAGCTGTCCATCGATGTTCTTCAGTCTTCTTTAGATGCCCACATGACGGATA
ATATTGAATTTGGCAGCGGACTGCTGCAGGATTACTTTGAGCAGGTCAAAGCTAAAAAAGTTTACGGTATCAATGATCTG
CTGCTTATCGGACTCTATTTTTATCAAAGTTCGTCTGATCACATTTACCTTGATGATACTTCTTTAGAAACTTTGGATAT
GCTGGCCGGCCGTCTGGTTCTTCAAACCAGATATATCGTCCCCAGTCATCTTTTTCTGCTGCGAGATGTCTTGCTGCAGT
GCAGCGGCCTGCTTTTACTGACCAAATCTTATCAGCATCTCTTAACCATTGTTCAGGAACTGAATACCATCATCAGTAAA
ACTCAGGACTACCAAAAGAAACCGCTGGTTGATATGATCGAATGGAAATATTATCTGTATGTGGATCAGGATTTCAGCGC
AGCTCAGCTGAAATATCAGCAGGCTGTGCAATTCTCTGTTATGATTGATGACGAGATTTTAAAAGAAAATTTAGAGAAAG
AATGGCGGAACGACAGCCTGCAGTTAAGAACATGA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (8-63)

• ComR tetratricopeptide (ComR_TPR) (72-295)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	49.669	99.342	0.493
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	44.792	94.737	0.424
comR	Streptococcus pyogenes MGAS8232	42.295	100	0.424
comR	Streptococcus pyogenes MGAS315	41.946	98.026	0.411
comR	Streptococcus suis P1/7	39.867	99.013	0.395
comR	Streptococcus suis 05ZYH33	39.867	99.013	0.395
comR	Streptococcus suis D9	37.459	100	0.378