Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   ES298_RS10375 Genome accession   NZ_CP038253
Coordinates   1993876..1994316 (-) Length   146 a.a.
NCBI ID   WP_001206580.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901929     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1988876..1999316
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES298_RS10345 (ES298_10885) - 1989185..1990060 (+) 876 WP_000669499.1 substrate-binding domain-containing protein -
  ES298_RS10350 (ES298_10890) pstC 1990178..1991041 (+) 864 WP_000595182.1 phosphate ABC transporter permease subunit PstC -
  ES298_RS10355 (ES298_10895) pstA 1991034..1991849 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  ES298_RS10360 (ES298_10900) pstB 1991851..1992603 (+) 753 WP_000536447.1 phosphate ABC transporter ATP-binding protein PstB -
  ES298_RS10365 (ES298_10905) phoU 1992618..1993268 (+) 651 WP_001245789.1 phosphate signaling complex protein PhoU -
  ES298_RS10370 (ES298_10910) - 1993309..1993761 (+) 453 Protein_2026 transposase -
  ES298_RS10375 (ES298_10915) comR 1993876..1994316 (-) 441 WP_001206580.1 helix-turn-helix transcriptional regulator Regulator
  ES298_RS10380 (ES298_10920) - 1994528..1995544 (+) 1017 WP_000415108.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  ES298_RS10385 (ES298_10925) galU 1995566..1996465 (+) 900 WP_000202232.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  ES298_RS10390 (ES298_10930) - 1996532..1997209 (-) 678 WP_000658498.1 rhomboid family intramembrane serine protease -
  ES298_RS10395 (ES298_10935) - 1997193..1997732 (-) 540 WP_000834344.1 5-formyltetrahydrofolate cyclo-ligase -
  ES298_RS10400 (ES298_10940) - 1997744..1998874 (-) 1131 WP_000885068.1 N-acetyldiaminopimelate deacetylase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17684.45 Da        Isoelectric Point: 4.9958

>NTDB_id=310406 ES298_RS10375 WP_001206580.1 1993876..1994316(-) (comR) [Streptococcus pneumoniae strain TVO_1901929]
MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRPILTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYF
LMRTPTYEDETIAQKKESVFAKIFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW

Nucleotide


Download         Length: 441 bp        

>NTDB_id=310406 ES298_RS10375 WP_001206580.1 1993876..1994316(-) (comR) [Streptococcus pneumoniae strain TVO_1901929]
TTGCGAGAGTTTGGCGAAAAAATTAAAAGATTACGTTTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTC
TGAATTAAGTATCCGTCAATTAATTAGAATTGAAAATGGAGAATCCAGACCAATACTAACAAAGTTAAAATATATTGCTG
AACGTTTGGAGGTTGAAGATTACAAGTTGATGCCAAGTTATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTC
TTGATGAGGACTCCTACATACGAAGATGAAACTATCGCCCAAAAGAAAGAGAGTGTTTTTGCTAAGATTTTTGAAGAGTA
TTATGATAGGCTACCTGAGGAAGAAAGATTTATCATCCCAAATTATTCATATCTAGCACTAGCGAACTACACAGTTCAAA
AATTACCAGAAAAGCTAGTTGAAATACTGTCCTTCTGGTGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(72-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

54.167

82.192

0.445
  comR Streptococcus pyogenes MGAS315

52.5

82.192

0.432
  comR Streptococcus mutans UA159

50.833

82.192

0.418
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

52.727

75.342

0.397
  comR Streptococcus suis P1/7

46.61

80.822

0.377
  comR Streptococcus suis 05ZYH33

46.61

80.822

0.377
  comR Streptococcus suis D9

45.763

80.822

0.37