Detailed information NTG0310256

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: ES276_RS07930
• Genome accession: NZ_CP038252
• Coordinates: 1563605..1564441 (-)
• Length: 278 a.a.
• NCBI ID: WP_238092981.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901936
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 1558605..1569441

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ES276_RS07920 (ES276_08435)	-	1560442..1561485 (-)	1044	WP_001812710.1	TIGR00341 family protein	-
ES276_RS07925 (ES276_08440)	-	1562089..1563033 (+)	945	WP_238092978.1	IS30-like element ISSpn8 family transposase	-
ES276_RS07930 (ES276_08450)	dprA/cilB/dalA	1563605..1564441 (-)	837	WP_238092981.1	DNA-processing protein DprA	Machinery gene
ES276_RS07935 (ES276_08455)	-	1564538..1565227 (-)	690	WP_238092985.1	sugar phosphate nucleotidyltransferase	-
ES276_RS07940 (ES276_08460)	-	1565239..1566117 (-)	879	WP_000837609.1	DMT family transporter	-
ES276_RS07945 (ES276_08465)	licA	1566107..1566976 (-)	870	WP_000411205.1	choline kinase LicA	-
ES276_RS07950 (ES276_08470)	-	1566993..1568015 (-)	1023	WP_000609894.1	ribitol-5-phosphate dehydrogenase	-
ES276_RS07955 (ES276_08475)	-	1568020..1568727 (-)	708	WP_000638501.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30680.29 Da
• Isoelectric Point: 5.2064

>NTDB_id=310256 ES276_RS07930 WP_238092981.1 1563605..1564441(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain TVO_1901936]
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAALQNGGKTIAV
IGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEEGRDV
FAIPASILDGLSDGCHHLIQEGAKLLTSGQDVLAEFEF

Nucleotide

• Length: 837 bp

>NTDB_id=310256 ES276_RS07930 WP_238092981.1 1563605..1564441(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain TVO_1901936]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATATCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGCATTGACACAGCAGCTCTTCAGAATGGCGGAAAAACCATTGCAGTG
ATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAATAAACGCTTGCAAGACTACATCGGCAATGACCATCTGGTTCT
AAGTGAATATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTGGACTTTGTCGTG
GTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACGTGTGAGCGAGCAATGGAAGAAGGACGCGATGTC
TTTGCTATTCCTGCTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGCAAAATTGCTCAC
CAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterProScan.

• DNA recombination-mediator protein A (DNA_processg_A) (75-267)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	97.872	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae D39	97.872	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae R6	97.872	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	97.872	100	0.993
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	96.454	100	0.978
dprA/cilB/dalA	Streptococcus mitis SK321	95.745	100	0.971
dprA	Streptococcus mutans UA159	62.143	100	0.626
dprA	Lactococcus lactis subsp. cremoris KW2	54.643	100	0.55
dprA	Staphylococcus aureus N315	36.749	100	0.374