Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   CH576_RS03640 Genome accession   NZ_CP031691
Coordinates   720552..721769 (+) Length   405 a.a.
NCBI ID   WP_105894636.1    Uniprot ID   -
Organism   Haemophilus influenzae strain P615-8618     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 715552..726769
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CH576_RS03620 (CH576_03620) corC 716518..717417 (-) 900 WP_116941683.1 CNNM family magnesium/cobalt transport protein CorC -
  CH576_RS03625 (CH576_03625) ampD 718040..718600 (-) 561 WP_042599472.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  CH576_RS03630 (CH576_03630) pilA 718715..719164 (+) 450 WP_105894634.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  CH576_RS03635 (CH576_03635) pilB 719161..720555 (+) 1395 WP_105894635.1 GspE/PulE family protein Machinery gene
  CH576_RS03640 (CH576_03640) pilC 720552..721769 (+) 1218 WP_105894636.1 type II secretion system F family protein Machinery gene
  CH576_RS03645 (CH576_03645) pilD 721766..722458 (+) 693 WP_105894637.1 A24 family peptidase Machinery gene
  CH576_RS03650 (CH576_03650) rho 722512..723774 (-) 1263 WP_005648966.1 transcription termination factor Rho -
  CH576_RS03655 (CH576_03655) metJ 724021..724338 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  CH576_RS03660 (CH576_03660) cueR 724352..724738 (-) 387 WP_005654127.1 Cu(I)-responsive transcriptional regulator -
  CH576_RS03665 (CH576_03665) - 724815..725021 (+) 207 WP_005656255.1 heavy-metal-associated domain-containing protein -
  CH576_RS03670 (CH576_03670) - 725096..725302 (+) 207 WP_005656255.1 heavy-metal-associated domain-containing protein -
  CH576_RS03675 (CH576_03675) - 725377..725583 (+) 207 WP_005656255.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 46083.25 Da        Isoelectric Point: 9.7235

>NTDB_id=310240 CH576_RS03640 WP_105894636.1 720552..721769(+) (pilC) [Haemophilus influenzae strain P615-8618]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLINHGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSHSLQIMLQAGIPLNQALDSFLPRTQTWQTKTLVNDIVLDKEVRSILQWVSQGY
AFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIAENYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFNM
GSVIQ

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=310240 CH576_RS03640 WP_105894636.1 720552..721769(+) (pilC) [Haemophilus influenzae strain P615-8618]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAGTTAATAAACCACGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAAC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGCAATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAATGAATGGCTTGAACGGCTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCCATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGTCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCCGAATTACCAACAATAACTGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTTTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCACAGTTTACAAATTATGTTACAGGCTGGCATTCCGCTTAATCAAGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAACCAAGACGCTTGTAAATGACATCGTATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGCTAT
GCGTTTTCTAATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTACAAATTGGCGAGCAAAGCGGAAA
ACTCGCTTTGATGCTAGAGCATATTGCTGAAAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAATGC
TAGAACCATTAATGATGGTGATCATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAATATG
GGTTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)

Type II secretion system (T2SS), protein F (T2SSF)

(266-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

97.291

100

0.975
  pilC Haemophilus influenzae 86-028NP

97.044

100

0.973
  pilC Glaesserella parasuis strain SC1401

38.25

98.765

0.378

Multiple sequence alignment