Detailed information NTG0309218

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DZL14_RS04470
• Genome accession: NZ_CP031640
• Coordinates: 876505..877341 (+)
• Length: 278 a.a.
• NCBI ID: WP_002995009.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS7888
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 871505..882341

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZL14_RS04440 (DZL14_04430)	-	871993..872427 (+)	435	WP_021340932.1	hypothetical protein	-
DZL14_RS04445 (DZL14_04435)	-	872477..873388 (-)	912	WP_011284791.1	diacylglycerol kinase family protein	-
DZL14_RS04450 (DZL14_04440)	-	873505..874155 (-)	651	WP_002984629.1	hemolysin III family protein	-
DZL14_RS04455 (DZL14_04445)	-	874152..874592 (-)	441	WP_002984627.1	DUF1836 domain-containing protein	-
DZL14_RS04460 (DZL14_04450)	ylqF	874811..875659 (+)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
DZL14_RS04465 (DZL14_04455)	-	875649..876440 (+)	792	WP_011888871.1	ribonuclease HII	-
DZL14_RS04470 (DZL14_04460)	dprA	876505..877341 (+)	837	WP_002995009.1	DNA-processing protein DprA	Machinery gene
DZL14_RS04475 (DZL14_04465)	topA	877448..879577 (+)	2130	WP_011284793.1	type I DNA topoisomerase	-
DZL14_RS09980	-	879652..880509 (-)	858	Protein_809	LysR family transcriptional regulator	-
DZL14_RS04490 (DZL14_04480)	-	880549..881094 (+)	546	Protein_810	PTS sugar transporter subunit IIC	-
DZL14_RS04495 (DZL14_04485)	-	881109..882101 (+)	993	WP_021340798.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30970.91 Da
• Isoelectric Point: 8.8230

>NTDB_id=309218 DZL14_RS04470 WP_002995009.1 876505..877341(+) (dprA) [Streptococcus pyogenes strain MGAS7888]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=309218 DZL14_RS04470 WP_002995009.1 876505..877341(+) (dprA) [Streptococcus pyogenes strain MGAS7888]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367