Detailed information NTG0309115

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DZM45_RS04820
• Genome accession: NZ_CP031638
• Coordinates: 952465..953301 (-)
• Length: 278 a.a.
• NCBI ID: WP_002995009.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS8347
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 947465..958301

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZM45_RS04795 (DZM45_04795)	-	947705..948697 (-)	993	WP_021340798.1	D-lactate dehydrogenase	-
DZM45_RS04800 (DZM45_04800)	-	948712..949257 (-)	546	Protein_874	PTS sugar transporter subunit IIC	-
DZM45_RS09200	-	949297..950154 (+)	858	Protein_875	LysR family transcriptional regulator	-
DZM45_RS04815 (DZM45_04815)	topA	950229..952358 (-)	2130	WP_011284793.1	type I DNA topoisomerase	-
DZM45_RS04820 (DZM45_04820)	dprA	952465..953301 (-)	837	WP_002995009.1	DNA-processing protein DprA	Machinery gene
DZM45_RS04825 (DZM45_04825)	-	953366..954157 (-)	792	WP_011888871.1	ribonuclease HII	-
DZM45_RS04830 (DZM45_04830)	ylqF	954147..954995 (-)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
DZM45_RS04835 (DZM45_04835)	-	955214..955654 (+)	441	WP_002984627.1	DUF1836 domain-containing protein	-
DZM45_RS04840 (DZM45_04840)	-	955651..956301 (+)	651	WP_002984629.1	hemolysin III family protein	-
DZM45_RS04845 (DZM45_04845)	-	956418..957329 (+)	912	WP_011284791.1	diacylglycerol kinase family protein	-
DZM45_RS04850 (DZM45_04850)	-	957379..957813 (-)	435	WP_021340932.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30970.91 Da
• Isoelectric Point: 8.8230

>NTDB_id=309115 DZM45_RS04820 WP_002995009.1 952465..953301(-) (dprA) [Streptococcus pyogenes strain MGAS8347]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=309115 DZM45_RS04820 WP_002995009.1 952465..953301(-) (dprA) [Streptococcus pyogenes strain MGAS8347]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367