Detailed information NTG0309008

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DZN59_RS04910
• Genome accession: NZ_CP031636
• Coordinates: 956784..957620 (-)
• Length: 278 a.a.
• NCBI ID: WP_002995009.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS10826
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 951784..962620

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZN59_RS04885 (DZN59_04885)	-	952024..953016 (-)	993	WP_021340798.1	D-lactate dehydrogenase	-
DZN59_RS04890 (DZN59_04890)	-	953031..953576 (-)	546	Protein_889	PTS sugar transporter subunit IIC	-
DZN59_RS09410	-	953616..954473 (+)	858	Protein_890	LysR family transcriptional regulator	-
DZN59_RS04905 (DZN59_04905)	topA	954548..956677 (-)	2130	WP_011284793.1	type I DNA topoisomerase	-
DZN59_RS04910 (DZN59_04910)	dprA	956784..957620 (-)	837	WP_002995009.1	DNA-processing protein DprA	Machinery gene
DZN59_RS04915 (DZN59_04915)	-	957685..958476 (-)	792	WP_011888871.1	ribonuclease HII	-
DZN59_RS04920 (DZN59_04920)	ylqF	958466..959314 (-)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
DZN59_RS04925 (DZN59_04925)	-	959533..959973 (+)	441	WP_002984627.1	DUF1836 domain-containing protein	-
DZN59_RS04930 (DZN59_04930)	-	959970..960620 (+)	651	WP_002984629.1	hemolysin III family protein	-
DZN59_RS04935 (DZN59_04935)	-	960737..961648 (+)	912	WP_011284791.1	diacylglycerol kinase family protein	-
DZN59_RS04940 (DZN59_04940)	-	961698..962132 (-)	435	WP_021340932.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30970.91 Da
• Isoelectric Point: 8.8230

>NTDB_id=309008 DZN59_RS04910 WP_002995009.1 956784..957620(-) (dprA) [Streptococcus pyogenes strain MGAS10826]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=309008 DZN59_RS04910 WP_002995009.1 956784..957620(-) (dprA) [Streptococcus pyogenes strain MGAS10826]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367