Detailed information NTG0308692

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DZR83_RS04850
• Genome accession: NZ_CP031630
• Coordinates: 947691..948527 (-)
• Length: 278 a.a.
• NCBI ID: WP_002995009.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS28271
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 942691..953527

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZR83_RS04825 (DZR83_04820)	-	942931..943923 (-)	993	WP_021340798.1	D-lactate dehydrogenase	-
DZR83_RS04830 (DZR83_04825)	-	943938..944483 (-)	546	Protein_886	PTS sugar transporter subunit IIC	-
DZR83_RS09335	-	944523..945380 (+)	858	Protein_887	LysR family transcriptional regulator	-
DZR83_RS04845 (DZR83_04840)	topA	945455..947584 (-)	2130	WP_146708221.1	type I DNA topoisomerase	-
DZR83_RS04850 (DZR83_04845)	dprA	947691..948527 (-)	837	WP_002995009.1	DNA-processing protein DprA	Machinery gene
DZR83_RS04855 (DZR83_04850)	-	948592..949383 (-)	792	WP_011888871.1	ribonuclease HII	-
DZR83_RS04860 (DZR83_04855)	ylqF	949373..950221 (-)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
DZR83_RS04865 (DZR83_04860)	-	950440..950880 (+)	441	WP_002984627.1	DUF1836 domain-containing protein	-
DZR83_RS04870 (DZR83_04865)	-	950877..951527 (+)	651	WP_002984629.1	hemolysin III family protein	-
DZR83_RS04875 (DZR83_04870)	-	951644..952555 (+)	912	WP_011284791.1	diacylglycerol kinase family protein	-
DZR83_RS04880 (DZR83_04875)	-	952605..953039 (-)	435	WP_021340932.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30970.91 Da
• Isoelectric Point: 8.8230

>NTDB_id=308692 DZR83_RS04850 WP_002995009.1 947691..948527(-) (dprA) [Streptococcus pyogenes strain MGAS28271]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=308692 DZR83_RS04850 WP_002995009.1 947691..948527(-) (dprA) [Streptococcus pyogenes strain MGAS28271]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367