Detailed information NTG0308434

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DZU27_RS07430
• Genome accession: NZ_CP031625
• Coordinates: 1455609..1456610 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain MGAS28533
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1450609..1461610

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZU27_RS07415 (DZU27_07410)	thrS	1450779..1452722 (-)	1944	WP_011284591.1	threonine--tRNA ligase	-
DZU27_RS07420 (DZU27_07415)	-	1453144..1454478 (-)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
DZU27_RS07425 (DZU27_07420)	-	1454480..1455478 (-)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
DZU27_RS07430 (DZU27_07425)	ccpA	1455609..1456610 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DZU27_RS07435 (DZU27_07430)	-	1456784..1457869 (+)	1086	WP_011284589.1	Xaa-Pro peptidase family protein	-
DZU27_RS07440 (DZU27_07435)	-	1457918..1458583 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DZU27_RS07445 (DZU27_07440)	-	1458594..1458971 (+)	378	WP_002985686.1	VOC family protein	-
DZU27_RS07450 (DZU27_07445)	-	1459116..1460042 (+)	927	WP_011017477.1	glycosyltransferase family 2 protein	-
DZU27_RS07455 (DZU27_07450)	-	1460253..1460936 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=308434 DZU27_RS07430 WP_002985680.1 1455609..1456610(-) (ccpA) [Streptococcus pyogenes strain MGAS28533]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=308434 DZU27_RS07430 WP_002985680.1 1455609..1456610(-) (ccpA) [Streptococcus pyogenes strain MGAS28533]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559