Detailed information NTG0308426

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DZU27_RS05240
• Genome accession: NZ_CP031625
• Coordinates: 998249..999085 (-)
• Length: 278 a.a.
• NCBI ID: WP_002995009.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS28533
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 993249..1004085

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZU27_RS05215 (DZU27_05215)	-	993489..994481 (-)	993	WP_021340798.1	D-lactate dehydrogenase	-
DZU27_RS05220 (DZU27_05220)	-	994496..995041 (-)	546	Protein_955	PTS sugar transporter subunit IIC	-
DZU27_RS09765	-	995081..995938 (+)	858	Protein_956	LysR family transcriptional regulator	-
DZU27_RS05235 (DZU27_05235)	topA	996013..998142 (-)	2130	WP_011284793.1	type I DNA topoisomerase	-
DZU27_RS05240 (DZU27_05240)	dprA	998249..999085 (-)	837	WP_002995009.1	DNA-processing protein DprA	Machinery gene
DZU27_RS05245 (DZU27_05245)	-	999150..999941 (-)	792	WP_011888871.1	ribonuclease HII	-
DZU27_RS05250 (DZU27_05250)	ylqF	999931..1000779 (-)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
DZU27_RS05255 (DZU27_05255)	-	1000998..1001438 (+)	441	WP_002984627.1	DUF1836 domain-containing protein	-
DZU27_RS05260 (DZU27_05260)	-	1001435..1002085 (+)	651	WP_002984629.1	hemolysin III family protein	-
DZU27_RS05265 (DZU27_05265)	-	1002202..1003113 (+)	912	WP_011284791.1	diacylglycerol kinase family protein	-
DZU27_RS05270 (DZU27_05270)	-	1003163..1003597 (-)	435	WP_021340932.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30970.91 Da
• Isoelectric Point: 8.8230

>NTDB_id=308426 DZU27_RS05240 WP_002995009.1 998249..999085(-) (dprA) [Streptococcus pyogenes strain MGAS28533]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=308426 DZU27_RS05240 WP_002995009.1 998249..999085(-) (dprA) [Streptococcus pyogenes strain MGAS28533]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367