Detailed information NTG0306959

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: EXA24_RS00340
• Genome accession: NZ_CP036376
• Coordinates: 50193..51101 (+)
• Length: 302 a.a.
• NCBI ID: WP_000912095.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain Sag153
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 45193..56101

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EXA24_RS00320 (EXA24_00320)	purE	45710..46198 (+)	489	WP_001182531.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
EXA24_RS00325 (EXA24_00325)	purK	46185..47276 (+)	1092	WP_001084008.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
EXA24_RS00330 (EXA24_00330)	-	47329..48720 (+)	1392	WP_001079797.1	hypothetical protein	-
EXA24_RS00335 (EXA24_00335)	purB	48742..50040 (+)	1299	WP_000572890.1	adenylosuccinate lyase	-
EXA24_RS00340 (EXA24_00340)	comR	50193..51101 (+)	909	WP_000912095.1	XRE family transcriptional regulator	Regulator
EXA24_RS00345 (EXA24_00345)	ruvB	51302..52300 (+)	999	WP_000196633.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
EXA24_RS00350 (EXA24_00350)	-	52452..52889 (+)	438	WP_000754818.1	low molecular weight protein-tyrosine-phosphatase	-
EXA24_RS00355 (EXA24_00355)	-	52896..53276 (+)	381	WP_000787702.1	membrane protein	-
EXA24_RS00360 (EXA24_00360)	-	53273..55051 (+)	1779	WP_001220907.1	acyltransferase family protein	-

Sequence

Protein

• Length: 302 a.a.
• Molecular weight: 35727.11 Da
• Isoelectric Point: 5.5329

>NTDB_id=306959 EXA24_RS00340 WP_000912095.1 50193..51101(+) (comR) [Streptococcus agalactiae strain Sag153]
MLKHFGSKVRKFRESQQVTREEFCGDESELSVRQLARIEAGESVPNLSKAHYIARNLGVSLDSLTAGASLELSKKYKELK
YLILRTPTYNDTDRLDLIEKYLDEIYLNFYDDLPEDEKIAIESIQSSLDIYISKSHHFGDDLIREYMNQIKRKKIYSIND
LLIIKLWQYKITASRYDPNIFKIDTFIGTIDKLLNQVKVLSIENLFLLRDVLIYSLGILFILAEYQQIENIINTLNDILI
KTQDFQKRPIIDMFEWKYQLFYKENREVAKRKYQESTLFAQLIGDQVLVTQLKEEWKADYIE

Nucleotide

• Length: 909 bp

>NTDB_id=306959 EXA24_RS00340 WP_000912095.1 50193..51101(+) (comR) [Streptococcus agalactiae strain Sag153]
ATGTTAAAACATTTTGGTAGTAAAGTAAGGAAGTTTAGGGAATCTCAACAGGTGACACGAGAAGAATTTTGTGGCGATGA
ATCAGAGTTATCGGTCCGACAGCTGGCTCGGATTGAAGCAGGAGAATCTGTTCCAAATTTATCTAAGGCGCATTATATCG
CTAGAAATCTAGGAGTTAGTTTAGATTCCTTAACAGCAGGAGCGAGTTTAGAACTGTCAAAAAAATATAAGGAATTAAAG
TATCTTATATTAAGGACGCCTACCTACAATGATACAGATAGACTTGATTTGATTGAAAAATATCTAGATGAGATTTATTT
AAATTTCTATGATGATTTACCTGAAGATGAAAAAATAGCAATTGAGTCCATACAAAGTTCTTTAGATATTTATATTTCTA
AAAGCCATCATTTTGGAGATGACCTGATTAGGGAATACATGAATCAAATTAAACGAAAAAAGATTTACTCTATCAATGAC
TTACTTATAATTAAACTATGGCAATATAAGATTACTGCTAGCAGGTATGATCCCAATATTTTTAAAATAGATACATTTAT
TGGTACTATAGATAAGTTGCTTAATCAAGTAAAGGTATTATCAATTGAAAACCTGTTTTTATTAAGGGATGTCCTCATTT
ATTCGTTAGGTATATTGTTTATATTAGCTGAATATCAGCAAATAGAAAATATAATAAATACTCTAAATGATATTTTAATA
AAAACTCAGGATTTTCAAAAGAGGCCAATAATAGATATGTTCGAATGGAAATATCAGTTGTTTTATAAAGAAAATAGGGA
AGTGGCTAAAAGAAAGTATCAGGAATCAACTCTTTTTGCTCAATTAATTGGCGATCAAGTTTTAGTTACACAGCTAAAAG
AGGAATGGAAAGCAGACTATATAGAATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (74-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	45.151	99.007	0.447
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	45.296	95.033	0.43
comR	Streptococcus pyogenes MGAS315	43.478	99.007	0.43
comR	Streptococcus pyogenes MGAS8232	41.914	100	0.421
comR	Streptococcus suis P1/7	42.424	98.344	0.417
comR	Streptococcus suis 05ZYH33	42.424	98.344	0.417
comR	Streptococcus suis D9	38.384	98.344	0.377