Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   DK237_RS07190 Genome accession   NZ_CP031377
Coordinates   1421876..1422580 (-) Length   234 a.a.
NCBI ID   WP_004298854.1    Uniprot ID   A0A0K2E6P6
Organism   Streptococcus suis strain ISU2614     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1416876..1427580
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK237_RS07170 (DK237_07370) - 1417091..1417546 (-) 456 WP_002935846.1 ATP-binding cassette domain-containing protein -
  DK237_RS07175 (DK237_07375) - 1417785..1418987 (+) 1203 Protein_1392 IS110 family transposase -
  DK237_RS07180 (DK237_07385) vicX 1419724..1420527 (-) 804 WP_009910233.1 MBL fold metallo-hydrolase Regulator
  DK237_RS07185 (DK237_07390) micB 1420534..1421883 (-) 1350 WP_009910235.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DK237_RS07190 (DK237_07395) micA 1421876..1422580 (-) 705 WP_004298854.1 response regulator YycF Regulator
  DK237_RS07195 (DK237_07400) - 1422774..1423535 (+) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  DK237_RS07200 (DK237_07405) - 1423546..1424385 (+) 840 WP_002935837.1 transporter substrate-binding domain-containing protein -
  DK237_RS07205 (DK237_07410) - 1424400..1425098 (+) 699 WP_053861430.1 amino acid ABC transporter permease -
  DK237_RS07210 (DK237_07415) - 1425113..1425772 (+) 660 WP_009910247.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26781.77 Da        Isoelectric Point: 4.8957

>NTDB_id=306351 DK237_RS07190 WP_004298854.1 1421876..1422580(-) (micA) [Streptococcus suis strain ISU2614]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=306351 DK237_RS07190 WP_004298854.1 1421876..1422580(-) (micA) [Streptococcus suis strain ISU2614]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACGCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTGTTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGTTGCCAGAATTGGACGGACTAGAGGTTGCTCGAACCATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAACCCTTCTCTAATCGCGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTCGCTAAGAAGCATGGCAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATACAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K2E6P6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.974

99.573

0.816
  vicR Streptococcus mutans UA159

80.426

100

0.808
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376

Multiple sequence alignment