Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   DK237_RS07185 Genome accession   NZ_CP031377
Coordinates   1420534..1421883 (-) Length   449 a.a.
NCBI ID   WP_009910235.1    Uniprot ID   A0A0Z8DHB7
Organism   Streptococcus suis strain ISU2614     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1415534..1426883
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK237_RS07170 (DK237_07370) - 1417091..1417546 (-) 456 WP_002935846.1 ATP-binding cassette domain-containing protein -
  DK237_RS07175 (DK237_07375) - 1417785..1418987 (+) 1203 Protein_1392 IS110 family transposase -
  DK237_RS07180 (DK237_07385) vicX 1419724..1420527 (-) 804 WP_009910233.1 MBL fold metallo-hydrolase Regulator
  DK237_RS07185 (DK237_07390) micB 1420534..1421883 (-) 1350 WP_009910235.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DK237_RS07190 (DK237_07395) micA 1421876..1422580 (-) 705 WP_004298854.1 response regulator YycF Regulator
  DK237_RS07195 (DK237_07400) - 1422774..1423535 (+) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  DK237_RS07200 (DK237_07405) - 1423546..1424385 (+) 840 WP_002935837.1 transporter substrate-binding domain-containing protein -
  DK237_RS07205 (DK237_07410) - 1424400..1425098 (+) 699 WP_053861430.1 amino acid ABC transporter permease -
  DK237_RS07210 (DK237_07415) - 1425113..1425772 (+) 660 WP_009910247.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51099.13 Da        Isoelectric Point: 4.5202

>NTDB_id=306350 DK237_RS07185 WP_009910235.1 1420534..1421883(-) (micB) [Streptococcus suis strain ISU2614]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSSQKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNTDSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKTDLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=306350 DK237_RS07185 WP_009910235.1 1420534..1421883(-) (micB) [Streptococcus suis strain ISU2614]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATCACAGATATGGCGAATTCTCTTAATGATCTGTCCGAA
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACGCGTCTGACTTCCATCCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGCTTTCTAGCCAAAAGC
AGGAGCAGTATCACCTGCTCGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTTTGACTTTACGTGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
CCTGATTTCTGGCTTGGTAGTCGTCTTGCATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTGTTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTTAAATCCTATCTAGAGGCTCTGGATGAGGGGGCGCTGACG
GAGTCTGTTGCACCGAGTTTTGTTAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTAAG
CTTATCGCGTATTGATAATCAAGTTGGTCAGATAGATGTTGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATACTGATTCTGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTAGATAATATCTTAAATAATGCCATTAAATATTCGCCAGATGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTATCAGACGAAGGTCTGGGGATTCCGAAAA
CAGATTTACCTAGAATTTTTGACCGATTTTATCGCGTAGACAAGGCACGATCTCGTGCCCAAGGCGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTGAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTGGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(96-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8DHB7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

70.183

97.105

0.682
  vicK Streptococcus mutans UA159

70.72

89.755

0.635

Multiple sequence alignment