Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DV428_RS03645 Genome accession   NZ_CP031243
Coordinates   704307..705527 (+) Length   406 a.a.
NCBI ID   WP_114908723.1    Uniprot ID   -
Organism   Haemophilus haemolyticus strain M19346     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 699307..710527
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV428_RS03620 - 699887..700684 (-) 798 WP_114908719.1 sulfite exporter TauE/SafE family protein -
  DV428_RS03625 rppH 700684..701274 (-) 591 WP_111696429.1 RNA pyrophosphohydrolase -
  DV428_RS03630 ampD 701801..702355 (-) 555 WP_114908720.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  DV428_RS03635 pilA 702470..702919 (+) 450 WP_114908721.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  DV428_RS03640 pilB 702916..704310 (+) 1395 WP_114908722.1 GspE/PulE family protein Machinery gene
  DV428_RS03645 pilC 704307..705527 (+) 1221 WP_114908723.1 type II secretion system F family protein Machinery gene
  DV428_RS03650 pilD 705524..706216 (+) 693 WP_114908724.1 A24 family peptidase Machinery gene
  DV428_RS03655 rho 706271..707533 (-) 1263 WP_005629550.1 transcription termination factor Rho -
  DV428_RS03660 metJ 707779..708096 (+) 318 WP_005634287.1 met regulon transcriptional regulator MetJ -
  DV428_RS03665 - 708110..708496 (-) 387 WP_111696423.1 Cu(I)-responsive transcriptional regulator -
  DV428_RS03670 - 708573..708779 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  DV428_RS03675 - 708864..709070 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  DV428_RS03680 - 709045..709131 (+) 87 Protein_699 heavy metal-associated domain-containing protein -
  DV428_RS03685 - 709156..709362 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46266.41 Da        Isoelectric Point: 9.9009

>NTDB_id=304571 DV428_RS03645 WP_114908723.1 704307..705527(+) (pilC) [Haemophilus haemolyticus strain M19346]
MTKKLFYYQGSNTLNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLSVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYNGNNAELPTITAILLSISNFLKQNTGILLFFALSFFLFYNFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDIVLDKEVRSILQWVSQG
YAFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEYIAENYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=304571 DV428_RS03645 WP_114908723.1 704307..705527(+) (pilC) [Haemophilus haemolyticus strain M19346]
ATGACTAAAAAACTATTTTATTATCAAGGTAGTAACACATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAATTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCAACATTGCTACAGTCCGCAATTCCGTTAAAAAACAGTCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAATGAATGGCTTGAACGACTGCTTCAATCCATTGAATCTGGTTT
AGCATTCTCACAAGCCATTGAACAACAAGGGAAATATCTCACTCAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CGGGTAAACTTTCCGTAGTTTGTAAAAAAATAGCCACGCATCGTAGCCAATCTTTAGCATTACAACGTAAATTACAGAAA
ATTATGTTGTACCCCTCAATGGTATTGGGAATTTCATTATTACTAACGCTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAATGGCAATAATGCCGAATTACCAACAATAACCGCAATATTGCTCTCTATATCCAATTTTCTTAAAC
AAAATACTGGCATTTTGCTATTTTTCGCTTTGAGTTTTTTTCTATTTTATAACTTCTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAGCTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAAGCTGGCGTACCGCTTAATCAGGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAACCAAGAAAACGCTTGTAAATGACATCGTATTAGATAAAGAAGTGCGGTCAATTTTGCAATGGGTTTCTCAAGGC
TATGCGTTTTCTAATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGTTACAAATTGGCGAGCAAAGCGG
AAAACTCGCTTTGATGCTCGAGTATATTGCTGAAAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCGCAAA
TGCTAGAACCATTAATGATGGTGATCATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

97.537

100

0.975
  pilC Haemophilus influenzae 86-028NP

97.044

100

0.97
  pilC Glaesserella parasuis strain SC1401

38.155

98.768

0.377

Multiple sequence alignment