Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   DV428_RS03650 Genome accession   NZ_CP031243
Coordinates   705524..706216 (+) Length   230 a.a.
NCBI ID   WP_114908724.1    Uniprot ID   -
Organism   Haemophilus haemolyticus strain M19346     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 700524..711216
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV428_RS03625 rppH 700684..701274 (-) 591 WP_111696429.1 RNA pyrophosphohydrolase -
  DV428_RS03630 ampD 701801..702355 (-) 555 WP_114908720.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  DV428_RS03635 pilA 702470..702919 (+) 450 WP_114908721.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  DV428_RS03640 pilB 702916..704310 (+) 1395 WP_114908722.1 GspE/PulE family protein Machinery gene
  DV428_RS03645 pilC 704307..705527 (+) 1221 WP_114908723.1 type II secretion system F family protein Machinery gene
  DV428_RS03650 pilD 705524..706216 (+) 693 WP_114908724.1 A24 family peptidase Machinery gene
  DV428_RS03655 rho 706271..707533 (-) 1263 WP_005629550.1 transcription termination factor Rho -
  DV428_RS03660 metJ 707779..708096 (+) 318 WP_005634287.1 met regulon transcriptional regulator MetJ -
  DV428_RS03665 - 708110..708496 (-) 387 WP_111696423.1 Cu(I)-responsive transcriptional regulator -
  DV428_RS03670 - 708573..708779 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  DV428_RS03675 - 708864..709070 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  DV428_RS03680 - 709045..709131 (+) 87 Protein_699 heavy metal-associated domain-containing protein -
  DV428_RS03685 - 709156..709362 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26703.76 Da        Isoelectric Point: 8.6826

>NTDB_id=304572 DV428_RS03650 WP_114908724.1 705524..706216(+) (pilD) [Haemophilus haemolyticus strain M19346]
MIYFAMFLLGGILGIALWFYLSGFITRLQQEIYATYVELFPQNFLSFQPSFSSIQQKKCGHILRYFLSVGVGFIFLQIAF
KDSIFAIWLGLTLIILWAISYLDWDYQLISTTPCLWLLTLGLFGADNAFSLLTLSESIKSAASFFIVFYAIYWIAKCYYR
KEAFGRGDYWLAMALGSFIHLETLPHFLLLASVLGICFSLIHKKKKEFLPFAPFMNLSAVIIYFVKYYWY

Nucleotide


Download         Length: 693 bp        

>NTDB_id=304572 DV428_RS03650 WP_114908724.1 705524..706216(+) (pilD) [Haemophilus haemolyticus strain M19346]
ATGATTTACTTCGCAATGTTTTTATTAGGCGGCATCTTAGGGATCGCATTGTGGTTCTACCTATCTGGTTTTATTACGCG
TTTGCAGCAAGAGATTTATGCGACTTACGTTGAATTATTTCCACAAAACTTTCTGTCATTTCAGCCTAGCTTTTCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGATATTTTTTAAGTGTTGGGGTAGGATTTATATTTTTACAAATTGCCTTC
AAGGACTCTATTTTCGCTATATGGCTAGGGCTCACACTTATTATCCTTTGGGCAATTAGTTATCTTGATTGGGATTATCA
ACTTATTTCTACGACTCCCTGTTTATGGTTACTTACTCTCGGTTTGTTTGGCGCAGACAATGCCTTTTCATTGCTTACGT
TATCTGAAAGCATAAAAAGTGCGGCTAGTTTTTTTATTGTTTTCTACGCAATCTATTGGATTGCAAAATGTTATTACAGA
AAAGAAGCCTTTGGACGGGGAGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCATTTAGAAACCTTACCGCACTT
TTTATTATTAGCCTCAGTGCTTGGAATATGTTTTTCGCTTATTCATAAGAAGAAAAAAGAATTTTTACCTTTTGCCCCTT
TTATGAACTTATCGGCTGTCATCATTTATTTCGTCAAATATTACTGGTATTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(92-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae 86-028NP

91.739

100

0.917
  pilD Haemophilus influenzae Rd KW20

90.435

100

0.904

Multiple sequence alignment