Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   ETT52_RS08820 Genome accession   NZ_CP035447
Coordinates   1738154..1738750 (-) Length   198 a.a.
NCBI ID   WP_011285268.1    Uniprot ID   Q48QW4
Organism   Streptococcus pyogenes strain emm97.1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1733154..1743750
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT52_RS08785 (ETT52_08775) - 1733215..1733520 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  ETT52_RS08790 (ETT52_08780) ruvX 1733532..1733951 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  ETT52_RS08795 (ETT52_08785) - 1733948..1734217 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  ETT52_RS08800 (ETT52_08790) spx 1734330..1734728 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  ETT52_RS08805 (ETT52_08795) recA 1735019..1736155 (-) 1137 WP_002992179.1 recombinase RecA Machinery gene
  ETT52_RS08810 (ETT52_08800) cinA 1736244..1737515 (-) 1272 WP_030126182.1 competence/damage-inducible protein A Machinery gene
  ETT52_RS08815 (ETT52_08805) - 1737584..1738144 (-) 561 WP_063812052.1 DNA-3-methyladenine glycosylase I -
  ETT52_RS08820 (ETT52_08810) ruvA 1738154..1738750 (-) 597 WP_011285268.1 Holliday junction branch migration protein RuvA Machinery gene
  ETT52_RS08825 (ETT52_08815) - 1738752..1739972 (-) 1221 WP_136026284.1 MFS transporter -
  ETT52_RS08830 (ETT52_08820) hexB 1739983..1741965 (-) 1983 WP_136026283.1 DNA mismatch repair endonuclease MutL Machinery gene

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21811.12 Da        Isoelectric Point: 6.2537

>NTDB_id=302829 ETT52_RS08820 WP_011285268.1 1738154..1738750(-) (ruvA) [Streptococcus pyogenes strain emm97.1]
MYDYIKGQLTKITAKYIVVETNGLGYIINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL
LALGYKAAELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=302829 ETT52_RS08820 WP_011285268.1 1738154..1738750(-) (ruvA) [Streptococcus pyogenes strain emm97.1]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAACAAATGGACTAGGCTATAT
TATCAATGTAGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAACTGGTAACTATTTACCTGCATCAAGTGATTCGTG
AGGATGCTCACTTGTTGTTTGGGTTTCATACGGAAGACGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCTGGCATT
GGCCCCACAACAGCTCTTGCTATTGTAGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTAATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAGGCAGCGGAATTGAAGAAAATTCGTGCCTTCTTTGAAGGAACCTCTGAAACGGCCGAACAATA
CATCAAATCAGCCCTTAAACTATTAATGAAAGGCTAG

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA N terminal domain (RuvA_N)

(1-61)

RuvA, C-terminal domain (RuvA_C)

(152-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q48QW4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

67.005

99.495

0.667
  ruvA Streptococcus pneumoniae R6

67.005

99.495

0.667
  ruvA Streptococcus pneumoniae D39

67.005

99.495

0.667
  ruvA Bacillus subtilis subsp. subtilis str. 168

41.379

100

0.424

Multiple sequence alignment