Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   DR994_RS07445 Genome accession   NZ_CP030927
Coordinates   1443485..1444180 (-) Length   231 a.a.
NCBI ID   WP_082309090.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CS9     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1438485..1449180
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DR994_RS07430 (DR994_07605) - 1439296..1439841 (-) 546 WP_022096992.1 GNAT family N-acetyltransferase -
  DR994_RS07435 (DR994_07610) - 1439907..1441169 (-) 1263 WP_022096991.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  DR994_RS07440 (DR994_07615) - 1441255..1443495 (-) 2241 WP_173940620.1 DNA internalization-related competence protein ComEC/Rec2 -
  DR994_RS07445 (DR994_07620) comEA 1443485..1444180 (-) 696 WP_082309090.1 helix-hairpin-helix domain-containing protein Machinery gene
  DR994_RS07450 (DR994_07625) - 1444288..1445043 (-) 756 WP_002948862.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  DR994_RS10370 - 1445534..1445772 (+) 239 Protein_1437 polysaccharide deacetylase family protein -
  DR994_RS10085 (DR994_07635) - 1445821..1446108 (+) 288 WP_134973405.1 peptidoglycan GlcNAc deacetylase -
  DR994_RS07460 (DR994_07640) - 1446158..1446910 (+) 753 WP_002948852.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  DR994_RS07465 (DR994_07645) - 1446927..1447196 (+) 270 WP_011226404.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24514.46 Da        Isoelectric Point: 4.6300

>NTDB_id=302377 DR994_RS07445 WP_082309090.1 1443485..1444180(-) (comEA) [Streptococcus thermophilus strain CS9]
MKEKILAYVKDNRLFVSVIAVLMVIFCFFLWMTCGAGNSMEAETSYTDVTALSTSSSKQSSQSLSEASSQSKTEGSEKVK
SKVTVDVKGAVVNPGVYTLKAGARVTDVIQEAGGMTEDADAKSVNLAASLSDEEVIYVANKDENVSVLDQTGTGQVSDKG
GQAVSKDGKINLNTATSEQLQTISGIGAKRTEDIIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESLYVA

Nucleotide


Download         Length: 696 bp        

>NTDB_id=302377 DR994_RS07445 WP_082309090.1 1443485..1444180(-) (comEA) [Streptococcus thermophilus strain CS9]
GTGAAGGAAAAGATTCTAGCCTATGTCAAAGATAATCGTCTGTTTGTGAGTGTCATCGCTGTACTGATGGTGATTTTTTG
CTTCTTTTTATGGATGACTTGTGGTGCCGGCAACAGCATGGAGGCGGAGACGTCTTATACAGATGTGACAGCTTTGTCAA
CGTCTTCATCCAAACAAAGTTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAAACCGAAGGAAGTGAAAAAGTTAAG
TCAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGTCAATCCAGGTGTCTATACGCTAAAGGCAGGCGCTAGGGTGACAGA
TGTCATTCAGGAAGCTGGAGGAATGACAGAAGATGCAGACGCTAAGAGTGTTAACTTAGCCGCAAGCTTGTCAGATGAAG
AGGTTATTTATGTAGCCAATAAAGATGAAAATGTTTCTGTCCTTGATCAAACAGGTACTGGTCAGGTCTCTGACAAAGGA
GGGCAGGCTGTATCTAAGGATGGCAAAATTAACTTAAATACAGCAACCTCAGAGCAGTTGCAAACCATTTCTGGAATTGG
AGCTAAGCGGACAGAGGATATCATTGCCTATCGTGAAAGTCATGGCGGCTTTCAGTCCGTAGATGACTTGAAAAATGTCT
CAGGAATTGGTGATAAAACATTAGATAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(85-138)

Helix-hairpin-helix motif (HHH_3)

(167-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

99.134

100

0.991
  comEA/celA/cilE Streptococcus mitis SK321

40.611

99.134

0.403
  comEA/celA/cilE Streptococcus pneumoniae D39

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae R6

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae Rx1

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus mitis NCTC 12261

37.719

98.701

0.372

Multiple sequence alignment