Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   ETT67_RS00675 Genome accession   NZ_CP035432
Coordinates   104249..104677 (+) Length   142 a.a.
NCBI ID   WP_136059362.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm11     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 99249..109677
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT67_RS00655 (ETT67_00655) - 101581..101946 (+) 366 WP_038433847.1 DUF1033 family protein -
  ETT67_RS00660 (ETT67_00660) comGA 102039..102977 (+) 939 WP_111688216.1 competence type IV pilus ATPase ComGA Machinery gene
  ETT67_RS00665 (ETT67_00665) comGB 102913..103946 (+) 1034 Protein_81 competence type IV pilus assembly protein ComGB -
  ETT67_RS00670 (ETT67_00670) comGC 103948..104274 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  ETT67_RS00675 (ETT67_00675) comGD 104249..104677 (+) 429 WP_136059362.1 competence type IV pilus minor pilin ComGD Machinery gene
  ETT67_RS00680 (ETT67_00680) comGE 104634..104918 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE Machinery gene
  ETT67_RS00685 (ETT67_00685) comGF 104911..105345 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  ETT67_RS00690 (ETT67_00690) comGG 105329..105655 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  ETT67_RS00695 (ETT67_00695) comGH 105753..106706 (+) 954 WP_136019764.1 class I SAM-dependent methyltransferase Machinery gene
  ETT67_RS00700 (ETT67_00700) - 106765..107961 (+) 1197 WP_023078999.1 acetate kinase -
  ETT67_RS00705 (ETT67_00705) - 108147..108455 (+) 309 WP_030126458.1 hypothetical protein -
  ETT67_RS00710 (ETT67_00710) proC 108538..109308 (-) 771 WP_023078993.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16283.02 Da        Isoelectric Point: 10.3481

>NTDB_id=301338 ETT67_RS00675 WP_136059362.1 104249..104677(+) (comGD) [Streptococcus pyogenes strain emm11]
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTE
GNSLTVPKSITVNHPYRLVIDQMGGSHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP

Nucleotide


Download         Length: 429 bp        

>NTDB_id=301338 ETT67_RS00675 WP_136059362.1 104249..104677(+) (comGD) [Streptococcus pyogenes strain emm11]
ATGAAAAAGCCCGTCTTAGCAATTAAAGCTTTTACTTTGCTTGAAACTTTACTAAGTTTGTCAGTGATGAGTTTCATTAT
ATTGGGATTGTCTGTACCAGTGACAAAAAGCTATCAAAAAGTAGAAGAGCATCTGTTTTTTAGCCATTTTGAACATTTGT
ATCGACATCAGCAAAAGTTAGCCATATTACAGCAAAAACAGCGCGTCTTGGATATTTCTTCAACAAAAATTGTTACAGAA
GGTAATAGCCTAACAGTTCCTAAATCAATAACAGTGAATCATCCTTATCGGTTAGTTATTGATCAGATGGGAGGCAGCCA
TTCCTTAGCCAAAATTATTTTTGACATGACTGATCGACGCTTTAAATACCAATTTTATCTAGGGAGTGGGAATTATCAAA
AAACAAGTCAAAGCTTACATAGCCCTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus mutans UA140

44.961

90.845

0.408
  comGD Streptococcus mutans UA159

44.961

90.845

0.408
  comGD/cglD Streptococcus mitis NCTC 12261

39.706

95.775

0.38
  comGD Streptococcus gordonii str. Challis substr. CH1

39.695

92.254

0.366