Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   DP112_RS00340 Genome accession   NZ_CP030125
Coordinates   55518..56417 (+) Length   299 a.a.
NCBI ID   WP_114866091.1    Uniprot ID   -
Organism   Streptococcus suis strain HA1003     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 50518..61417
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DP112_RS00320 (DP112_00320) - 51652..52476 (+) 825 WP_114866089.1 ABC transporter ATP-binding protein -
  DP112_RS00325 (DP112_00325) - 52469..53212 (+) 744 WP_044763137.1 ABC transporter permease -
  DP112_RS11060 - 53264..53437 (+) 174 WP_164503891.1 hypothetical protein -
  DP112_RS00330 (DP112_00330) ruvB 53721..54722 (+) 1002 WP_105118966.1 Holliday junction branch migration DNA helicase RuvB -
  DP112_RS00335 (DP112_00335) - 54790..55413 (+) 624 WP_114866090.1 HAD-IA family hydrolase -
  DP112_RS00340 (DP112_00340) comR 55518..56417 (+) 900 WP_114866091.1 helix-turn-helix domain-containing protein Regulator
  DP112_RS00345 (DP112_00345) - 56634..57854 (+) 1221 WP_114866092.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  DP112_RS00355 (DP112_00355) - 58045..59568 (+) 1524 WP_114866093.1 quinol oxidase -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35336.18 Da        Isoelectric Point: 4.2843

>NTDB_id=299459 DP112_RS00340 WP_114866091.1 55518..56417(+) (comR) [Streptococcus suis strain HA1003]
MNDKEFGQCVRQLRETASLTREQFCDDELELSVRQLSRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYENEELMEKRADMMTEIYDDYYDDLPEEEKIAIDAIQSIIDVFETKTAEFGQDILEDYFEQIQRKNQFSAND
LLIIRLYLINLRMEIKQSSDFQHFLELVEKLPSQVELIESGELFILRDVMLTSIGILGEHEEYGKIPPLFDALDRIMVST
QDFQKKPILNLLKWKYELYVNNDSEEARRFYEEAVMFAKLIGDSHLVEKLESSWREEEK

Nucleotide


Download         Length: 900 bp        

>NTDB_id=299459 DP112_RS00340 WP_114866091.1 55518..56417(+) (comR) [Streptococcus suis strain HA1003]
ATGAACGATAAGGAATTTGGACAATGTGTACGTCAACTTCGAGAAACCGCTAGTCTGACACGTGAACAGTTTTGTGATGA
TGAACTGGAGCTCTCCGTCCGCCAATTAAGCCGTATCGAAGCAGGTACTTCTAAGCCGACTTTTTCAAAAATCCAATATA
TCGCAACCCGCTTAGGCATGGGGCTCTATGAGCTTATGCCTGATTATGTATCCTTGCCAGAAAGATACTCCAAACTGAAA
TTTGATGTCCTCCGTACACCGACTTATGAAAATGAGGAATTGATGGAAAAACGGGCAGATATGATGACAGAAATCTATGA
TGACTATTATGATGACTTGCCTGAAGAAGAGAAAATAGCGATTGATGCCATTCAATCTATTATTGATGTATTTGAAACGA
AGACAGCAGAATTTGGTCAAGATATTCTAGAAGATTATTTTGAACAAATCCAAAGAAAAAACCAATTTTCAGCCAATGAT
TTGTTGATAATTCGACTCTATTTAATCAATTTGAGAATGGAAATTAAACAGAGCAGTGATTTTCAGCACTTTTTAGAGTT
GGTGGAAAAGTTACCAAGCCAAGTAGAATTGATTGAATCTGGAGAATTATTTATTTTAAGAGATGTGATGCTGACGTCGA
TAGGGATTCTTGGCGAACATGAAGAATATGGCAAGATACCTCCACTTTTTGATGCTCTAGATAGAATCATGGTTTCAACT
CAAGATTTTCAAAAGAAACCCATTCTCAATCTGCTTAAGTGGAAATATGAGTTGTATGTGAACAATGATAGCGAGGAGGC
TAGACGGTTTTATGAAGAAGCAGTTATGTTCGCAAAATTAATAGGAGACTCCCATTTAGTAGAAAAATTAGAATCATCAT
GGAGAGAAGAGGAAAAGTGA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-294)

Helix-turn-helix domain (HTH_31)

(5-60)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

67.797

98.662

0.669
  comR Streptococcus suis 05ZYH33

67.797

98.662

0.669
  comR Streptococcus suis D9

61.204

100

0.612
  comR Streptococcus mutans UA159

41.806

100

0.418
  comR Streptococcus pyogenes MGAS8232

37.71

99.331

0.375
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

38.542

96.321

0.371
  comR Streptococcus pyogenes MGAS315

36.486

98.997

0.361

Multiple sequence alignment