Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   DK875_RS02845 Genome accession   NZ_CP030020
Coordinates   574227..574931 (+) Length   234 a.a.
NCBI ID   WP_002935840.1    Uniprot ID   A0A0M9FML3
Organism   Streptococcus suis strain ISU2514     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 569227..579931
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK875_RS02825 (DK875_02955) - 571035..571694 (-) 660 WP_002935828.1 amino acid ABC transporter permease -
  DK875_RS02830 (DK875_02960) - 571709..572407 (-) 699 WP_002935835.1 amino acid ABC transporter permease -
  DK875_RS02835 (DK875_02965) - 572422..573261 (-) 840 WP_002935837.1 transporter substrate-binding domain-containing protein -
  DK875_RS02840 (DK875_02970) - 573272..574033 (-) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  DK875_RS02845 (DK875_02975) micA 574227..574931 (+) 705 WP_002935840.1 response regulator YycF Regulator
  DK875_RS02850 (DK875_02980) micB 574924..576273 (+) 1350 WP_002935841.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DK875_RS02855 (DK875_02985) vicX 576280..577083 (+) 804 WP_002935843.1 MBL fold metallo-hydrolase Regulator
  DK875_RS02860 (DK875_02995) - 577820..579022 (-) 1203 WP_280635075.1 IS110-like element ISSsu7 family transposase -
  DK875_RS02865 (DK875_03000) - 579261..579716 (+) 456 WP_002935846.1 ATP-binding cassette domain-containing protein -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26751.75 Da        Isoelectric Point: 4.8957

>NTDB_id=298359 DK875_RS02845 WP_002935840.1 574227..574931(+) (micA) [Streptococcus suis strain ISU2514]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDAPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=298359 DK875_RS02845 WP_002935840.1 574227..574931(+) (micA) [Streptococcus suis strain ISU2514]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACGCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTATTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGTTGCCAGAATTGGACGGACTAGAGGTTGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAACCCTTCTCTAATCGCGA
ATTACAGGCGCGTGTTAAGGCTCTTCTTCGCCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTTGCTAAGAAGCATGGTAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATGCAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FML3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.545

99.573

0.812
  vicR Streptococcus mutans UA159

80

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376

Multiple sequence alignment