Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   A7J09_RS08260 Genome accession   NZ_CP030015
Coordinates   1709181..1709885 (-) Length   234 a.a.
NCBI ID   WP_029178655.1    Uniprot ID   -
Organism   Streptococcus suis strain ISU2812     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1704181..1714885
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7J09_RS08240 (A7J09_08395) - 1704397..1704852 (-) 456 WP_029178534.1 ATP-binding cassette domain-containing protein -
  A7J09_RS08245 (A7J09_08400) - 1705091..1706293 (+) 1203 WP_148124345.1 IS110 family transposase -
  A7J09_RS08250 (A7J09_08410) vicX 1707029..1707832 (-) 804 WP_002935843.1 MBL fold metallo-hydrolase Regulator
  A7J09_RS08255 (A7J09_08415) micB 1707839..1709188 (-) 1350 WP_029178656.1 cell wall metabolism sensor histidine kinase VicK Regulator
  A7J09_RS08260 (A7J09_08420) micA 1709181..1709885 (-) 705 WP_029178655.1 response regulator YycF Regulator
  A7J09_RS08265 (A7J09_08425) - 1710079..1710840 (+) 762 WP_029178654.1 amino acid ABC transporter ATP-binding protein -
  A7J09_RS08270 (A7J09_08430) - 1710851..1711690 (+) 840 WP_029178653.1 transporter substrate-binding domain-containing protein -
  A7J09_RS08275 (A7J09_08435) - 1711705..1712403 (+) 699 WP_029174867.1 amino acid ABC transporter permease -
  A7J09_RS08280 (A7J09_08440) - 1712418..1713077 (+) 660 WP_014637676.1 amino acid ABC transporter permease -
  A7J09_RS08285 (A7J09_08445) - 1713200..1713475 (+) 276 WP_029174866.1 acyltransferase family protein -
  A7J09_RS08290 (A7J09_08450) - 1713439..1714233 (+) 795 WP_161606664.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26795.80 Da        Isoelectric Point: 4.8957

>NTDB_id=298271 A7J09_RS08260 WP_029178655.1 1709181..1709885(-) (micA) [Streptococcus suis strain ISU2812]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLLILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=298271 A7J09_RS08260 WP_029178655.1 1709181..1709885(-) (micA) [Streptococcus suis strain ISU2812]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACGCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTATTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGTTGCCAGAATTGGACGGACTAGAGGTTGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAACCCTTCTCTAATCGCGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGCTCATTCTGCCTGATGCGTTTGTTGCTAAGAAGCATGGTAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAGATTGAAGATACAC
CAAGCCGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.974

99.573

0.816
  vicR Streptococcus mutans UA159

80.426

100

0.808
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.348

98.291

0.436
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.397

100

0.389

Multiple sequence alignment