Detailed information NTG0297684

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: EQH18_RS05895
• Genome accession: NZ_CP035262
• Coordinates: 1195629..1196477 (-)
• Length: 282 a.a.
• NCBI ID: WP_000705304.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901923
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 1190629..1201477

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH18_RS05875 (EQH18_06205)	metG	1190879..1192516 (-)	1638	WP_000021543.1	methionine--tRNA ligase	-
EQH18_RS05880 (EQH18_06210)	-	1192584..1193258 (-)	675	WP_000903082.1	CatA-like O-acetyltransferase	-
EQH18_RS05885 (EQH18_06215)	-	1193317..1193616 (-)	300	WP_001138382.1	hypothetical protein	-
EQH18_RS05890 (EQH18_06220)	-	1194104..1195057 (+)	954	WP_001155321.1	IS30-like element ISSpn8 family transposase	-
EQH18_RS05895 (EQH18_06225)	dprA/cilB/dalA	1195629..1196477 (-)	849	WP_000705304.1	DNA-processing protein DprA	Machinery gene
EQH18_RS05900 (EQH18_06230)	-	1196573..1197262 (-)	690	WP_000643970.1	sugar phosphate nucleotidyltransferase	-
EQH18_RS05905 (EQH18_06235)	-	1197274..1198152 (-)	879	WP_000837614.1	DMT family transporter	-
EQH18_RS05910 (EQH18_06240)	licA	1198142..1199011 (-)	870	WP_000411218.1	choline kinase LicA	-
EQH18_RS05915 (EQH18_06245)	-	1199028..1200050 (-)	1023	WP_000609886.1	ribitol-5-phosphate dehydrogenase	-
EQH18_RS05920 (EQH18_06250)	-	1200055..1200762 (-)	708	WP_000638502.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31076.75 Da
• Isoelectric Point: 5.4047

>NTDB_id=297684 EQH18_RS05895 WP_000705304.1 1195629..1196477(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain TVO_1901923]
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPGSILDGLSDGCHHLIQEGAKLLTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=297684 EQH18_RS05895 WP_000705304.1 1195629..1196477(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain TVO_1901923]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATATCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAATAAACGCTTGCAAGACTACATCGGCAATGA
CCATCTGGTTCTAAGTGAATATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACGTGTGAGCGAGCAATGGAAGAA
GGACGCGATGTCTTTGCTATTCCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGC
AAAATTGCTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterProScan.

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae D39	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae R6	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	99.645	100	0.996
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	98.227	100	0.982
dprA/cilB/dalA	Streptococcus mitis SK321	97.518	100	0.975
dprA	Streptococcus mutans UA159	63.214	99.291	0.628
dprA	Lactococcus lactis subsp. cremoris KW2	55.357	99.291	0.55
dprA	Staphylococcus aureus N315	37.456	100	0.376