Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   EQH26_RS00620 Genome accession   NZ_CP035254
Coordinates   100434..101783 (+) Length   449 a.a.
NCBI ID   WP_000801632.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901932     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 95434..106783
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH26_RS00600 (EQH26_00610) - 96341..96823 (+) 483 WP_001232094.1 stage II sporulation protein M -
  EQH26_RS00605 (EQH26_00615) - 96820..97416 (+) 597 WP_000687787.1 ATP-binding cassette domain-containing protein -
  EQH26_RS00610 (EQH26_00620) - 97397..97888 (+) 492 WP_000671990.1 hypothetical protein -
  EQH26_RS00615 (EQH26_00625) comA 98268..100421 (+) 2154 WP_000668286.1 peptide cleavage/export ABC transporter ComA Regulator
  EQH26_RS00620 (EQH26_00630) comB 100434..101783 (+) 1350 WP_000801632.1 competence pheromone export protein ComB Regulator
  EQH26_RS00625 (EQH26_00635) purC 101953..102660 (+) 708 WP_000043303.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  EQH26_RS10890 (EQH26_00640) - 102671..102805 (+) 135 WP_000429436.1 hypothetical protein -
  EQH26_RS00630 (EQH26_00645) - 102862..106587 (+) 3726 WP_000361211.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49695.60 Da        Isoelectric Point: 5.2590

>NTDB_id=296791 EQH26_RS00620 WP_000801632.1 100434..101783(+) (comB) [Streptococcus pneumoniae strain TVO_1901932]
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGELLVQYQEGVEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQEGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTVKSAIETGASLAGQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=296791 EQH26_RS00620 WP_000801632.1 100434..101783(+) (comB) [Streptococcus pneumoniae strain TVO_1901932]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAAAAGGAGATGAGTTTGTCCACTAGAGCTACTGTCG
AACCTAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGAGCTTTTGGTTCAATACCAAGAAGGGGTAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGAAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGTTAAGTCAGCTATTGAAACAGGTGCTTCCTTGGCCGGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTATAAGTCTCAGGGCGAGGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACACTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCAAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCCTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTTCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
TCTACAGATGATTACGGGCAAGAAAAGTTATCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae TIGR4

98.664

100

0.987
  comB Streptococcus pneumoniae D39

98.441

100

0.984
  comB Streptococcus pneumoniae R6

98.441

100

0.984
  comB Streptococcus pneumoniae Rx1

98.441

100

0.984
  comB Streptococcus mitis SK321

94.655

100

0.947
  comB Streptococcus mitis NCTC 12261

94.209

100

0.942
  comB Streptococcus gordonii str. Challis substr. CH1

55.778

100

0.559