Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   EQH37_RS10060 Genome accession   NZ_CP035243
Coordinates   1980516..1980920 (-) Length   134 a.a.
NCBI ID   WP_223842268.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901946     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1975516..1985920
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH37_RS10030 (EQH37_10585) - 1975825..1976700 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  EQH37_RS10035 (EQH37_10590) pstC 1976818..1977681 (+) 864 WP_000595182.1 phosphate ABC transporter permease subunit PstC -
  EQH37_RS10040 (EQH37_10595) pstA 1977674..1978489 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  EQH37_RS10045 (EQH37_10600) pstB 1978491..1979243 (+) 753 WP_000536449.1 phosphate ABC transporter ATP-binding protein PstB -
  EQH37_RS10050 (EQH37_10605) phoU 1979258..1979908 (+) 651 WP_001245781.1 phosphate signaling complex protein PhoU -
  EQH37_RS10055 (EQH37_10610) - 1979949..1980401 (+) 453 Protein_1966 transposase -
  EQH37_RS10060 (EQH37_10615) comR 1980516..1980920 (-) 405 WP_223842268.1 helix-turn-helix transcriptional regulator Regulator
  EQH37_RS10065 (EQH37_10620) - 1981168..1982184 (+) 1017 WP_054366240.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  EQH37_RS10070 (EQH37_10625) galU 1982206..1983105 (+) 900 WP_000202218.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  EQH37_RS10075 (EQH37_10630) - 1983172..1983849 (-) 678 WP_000658495.1 rhomboid family intramembrane serine protease -
  EQH37_RS10080 (EQH37_10635) - 1983833..1984372 (-) 540 WP_000834344.1 5-formyltetrahydrofolate cyclo-ligase -
  EQH37_RS10085 (EQH37_10640) - 1984384..1985514 (-) 1131 WP_000885068.1 N-acetyldiaminopimelate deacetylase -

Sequence

Protein


Download         Length: 134 a.a.        Molecular weight: 16261.66 Da        Isoelectric Point: 4.5242

>NTDB_id=295809 EQH37_RS10060 WP_223842268.1 1980516..1980920(-) (comR) [Streptococcus pneumoniae strain TVO_1901946]
MAKKISRSEFCGDESELSIRQLIRIENGESRPILTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETI
TQKKESVFDKIFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEILSFW

Nucleotide


Download         Length: 405 bp        

>NTDB_id=295809 EQH37_RS10060 WP_223842268.1 1980516..1980920(-) (comR) [Streptococcus pneumoniae strain TVO_1901946]
TTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTCTGAATTAAGTATCCGTCAATTAATTAGAATTGAAAA
TGGAGAATCCAGACCAATACTAACAAAGTTAAAATATATTGCTGAACGTTTGGAGGTTGAAGATTACAAGTTGATGCCAA
GTTATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTCTTGATGAGGACTCCTACATACGAAGATGAAACTATC
ACCCAAAAGAAAGAGAGTGTTTTTGATAAGATTTTTGAAGAGTATTATGATAGGCTACCTGAGGAAGAAAGATTTATCAT
CCCAAATTATTCATATCTGGCACTAACGAACTACACAGTTCAAAAATTACCAGAAAAGCTAGTTGAAATACTGTCCTTCT
GGTGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(60-107)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

54.63

80.597

0.44
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

54.717

79.104

0.433
  comR Streptococcus pyogenes MGAS315

52.778

80.597

0.425
  comR Streptococcus mutans UA159

50

80.597

0.403
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

48.039

76.119

0.366
  comR Streptococcus suis P1/7

46.226

79.104

0.366
  comR Streptococcus suis 05ZYH33

46.226

79.104

0.366

Multiple sequence alignment